Abstract
New heterocycle compound 2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene (1), designed using 5-iodo-2-methylbenzoic acid (2) as the starting material is successfully obtained via the multiple synthesis route and finally characterized by IR, 1H NMR, and single crystal X-ray crystallography. In addition, the in vitro anticancer activity of compound 1 on three human lung cancer cells (H20, H2227, and H69) is further determined, which suggests that compound 1 may be a potential anticancer agent.
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21 May 2024
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1134/S0022476624040309
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Funding
This work was supported by grants from Health and Family Planning Commission of Inner Mongolia Autonomous Region (201703143) and Inner Mongolia Autonomous Region Natural Science Foundation (2018MS08113).
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This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1134/S0022476624040309
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Zhou, L.P., Qiu, F., Zhang, Z.F. et al. RETRACTED ARTICLE: SYNTHESIS, CRYSTAL STRUCTURE, ANTI-LUNG CANCER ACTIVITY OF 2-(4-FLUOROPHENYL)-5- (5-IODO-2-METHYLBENZYL)THIOPHENE. J Struct Chem 61, 1111–1116 (2020). https://doi.org/10.1134/S0022476620070148
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DOI: https://doi.org/10.1134/S0022476620070148