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RETRACTED ARTICLE: Two Novel Pyran Derivatives: Crystal Structures, Anti-Liver Cancer Activity, and Docking Study

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This article was retracted on 01 March 2024

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Abstract

The synthesis and characterization of two new pyran derivatives (1 and 2) are characterized by infrared (IR) and 1H nuclear magnetic resonance spectroscopy (1H NMR), high resolution mass spectrum (HRMS), and single crystal X-ray crystallography. The anticancer activity of compounds is investigated against four human liver cancer cells (Hep G2, SMMC-7721, HHCC, and HB611) by 3-(4,5)-dimethylthiahiazo(-z-y1)-3,5-di-phenytetrazoliumbromide (MTT) assay. Furthermore, molecular docking studies support the biological assay data and suggest that the two compounds have a similar interaction strength with protein.

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Authors and Affiliations

  1. Department of Oncology, The First People’s Hospital of Changzhou, Changzhou, P. R. China

    D. Li

  2. Department of Chinese Medicine, Changzhou Tianning Street Community Hospital, Changzhou, P. R. China

    H. -Y. Wang

  3. Department of Interventional Radiology, The First People’s Hospital of Changzhou, Changzhou, P. R. China

    W. -H. Chen

  4. Department of Oncology, Central Hospital of China National Petroleum and Natural Gas Corporation, Langfang, Hebei, P. R. China

    Q. Guo

Authors
  1. D. Li
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  2. H. -Y. Wang
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  3. W. -H. Chen
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  4. Q. Guo
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Corresponding author

Correspondence to W. -H. Chen.

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The authors declare that they have no conflict of interests.

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Text © The Author(s), 2020, published in Zhurnal Strukturnoi Khimii, 2020, Vol. 61, No. 4, pp. 617–622.

This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1134/S0022476624030260

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Li, D., Wang, H.Y., Chen, W.H. et al. RETRACTED ARTICLE: Two Novel Pyran Derivatives: Crystal Structures, Anti-Liver Cancer Activity, and Docking Study. J Struct Chem 61, 587–592 (2020). https://doi.org/10.1134/S0022476620040125

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  • DOI: https://doi.org/10.1134/S0022476620040125

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