Abstract
Electrospray ionization mass spectrometry is used to study thymidine solutions in the presence of copper ions and EDTA. The results show formation of thymidine–EDTA complexes in the absence of CuCl2, and the existence of thymidine–EDTA–CuCl2 complexes in a CuCl2 and EDTA containing thymidine solution. The stoichiometry of the complexes is determined.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
D. D. Perrin, Organic Complexing Reagents: Structure, Behavior, and Application to Inorganic Analysis, Interscience Publishers, John Wiley & Sons, Canberra, New York (1964).
N. M. Dyatlova, V. Ya. Temkina, and K. I. Popov, Complexones and Complexonates of Metals [in Russian], Khimiya, Moscow (1988).
R. Přibil, Analytical Applications of EDTA and Related Compounds, Pergamon Press, Oxford (1972).
H. Liu, L. Xu, G.-G. Gao, F.-Y. Li, Y.-Y. Yang, Z.-K. Li, and Yu. Sun, J. Solid State Chem., 180, 1664 (2007).
J. R. Brody and S. E. Kern, Anal. Biochem., 333, 1 (2004).
M. A. Semenov, T. V. Bol’bukh, A. A. Krasnitskaya, and V. Ya. Maleev, Probl. Kriobiol., No. 4, 17 (1994).
J. C. Joyner, J. Reichfield, and J. A. Cowan, J. Am. Chem. Soc., 133, 15613 (2011).
D. Desbouis, I. P. Troitsky, M. J. Belousoff, L. Spiccia, and B. Graham, Coord. Chem. Rev., 256, 897 (2012).
S. Ji, M. Chen, H. Li, G. Gan, and W. Li, Spectochim. Acta, Part A, 88, 124 (2012).
M. Chen, H. Li, Q. Li, and Zh. Xu, Spectrochim. Acta, Part A, 75, 1566 (2010).
G.-L. Gan, H. Chao, S.-B. Ji, L.-L. Chen, and H. Li, Spectrochim. Acta, Part A, 97, 297 (2012).
W. Saenger, Principles of Nucleic Acid Structure, Springer, New York (1984).
A. Krueger, E. Protozanova, and M. D. Frank-Kamenetskii, Biophys. J., 90, 3091 (2006).
GOST (State standart) 10398-76: Reagents and Highly Purified Substances. Complexometric Method for Determining the Content of the Basic Substance (1977).
A. A. El-Sherif, M. M. Shoukry, W. M. Hosny, and M. G. Abd-Elmoghny, J. Solution Chem., 41, 813 (2012).
W. Henderson and J. S. McIndoe, Mass Spectrometry of Inorganic, Coordination and Organometallic Compounds, John Wiley & Sons, England (2005).
A. T. Lebedev, Mass Spectrometry in Organic Chemistry [in Russian], Binom. Laboratoriya Znanii, Moscow (2003).
A. Snyder (ed.), Biochemical and Biotechnological Applications of Electrospray Ionization Mass Spectrometry, vol. 619 of ACS Symposium Series, American Chemical Society, Washington, DC (1996).
J. H. Banoub and P. A. Limbach, Mass Spectrometry of Nucleosides and Nucleic Acids, CRC Press, Taylor and Francis Group, FL (2009).
F. Rosu, V. Gabelica, C. Houssier, and E. De Pauw, Nucleic Acids Res., 30, No. 16, e82 (2002).
L. Oehlers, C. L. Mazzitelli, J. S. Brodbelt, M. Rodriguez, and S. Kerwin, J. Am. Soc. Mass Spectrom., 15, 1593 (2004).
T.-Y. Yen, M. J. Charles, and R. D. Voyksner, J. Am. Soc. Mass Spectrom., 7, 1106 (1996).
F. Peral and E. Gallego, J. Mol. Struct.: THEOCHEM, 372, 101 (1995).
D. Armentano, G. De Munno, L. Di Donna, G. Sindona, G. Giorgi, and L. Salvini, J. Am. Soc. Mass Spectrom., 15, 268 (2004).
A. I. Nikolaev and S. V. Paston, J. Phys.: Conf. Ser., 661, 012019 (2015).
F. Aradi and A. Foldesi, Magn. Reson. Chem., 27, 592 (1989).
F. Aradi and A. Foldesi, Magn. Reson. Chem., 25, 892 (1987).
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © 2017 S. V. Paston, A. I. Nikolaev, P. A. Ushkov.
Translated from Zhurnal Strukturnoi Khimii, Vol. 58, No. 2, pp. 410–416, February–March, 2017.
Rights and permissions
About this article
Cite this article
Paston, S.V., Nikolaev, A.I. & Ushkov, P.A. EDTA, thymidine, and Cu2+ ion complexes from mass spectrometry data. J Struct Chem 58, 392–398 (2017). https://doi.org/10.1134/S0022476617020251
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0022476617020251