Abstract
The X-ray diffraction study of an indoline alkaloid, pseudokopsinine, extracted from the plant Vinca erecta and its mono- and double salts is performed. The experimentally determined positions of Н atoms suggest the sp 3 hybridization of the indoline nitrogen atom in the base and salts. The pseudokopsinine base and double salt have an intramolecular Н bond between the NH group proton and the ether oxygen atom of the methoxycarbonyl group, which is absent in the monosalt and the related indolines. The intermolecular Н bonds and/or the packing efficiency cause a conformational change in F and Е heterocycles in the indoline hetero framework of pseudokopsinine salts in comparison with that observed in the base.
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Original Russian Text © 2017 Sh. M. Adizov, B. Tashkhodzhaev, R. Zh. Kunafiev, M. M. Mirzaeva, P. Kh. Yuldashev.
Translated from Zhurnal Strukturnoi Khimii, Vol. 58, No. 2, pp. 308–313, February–March, 2017.
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Adizov, S.M., Tashkhodzhaev, B., Kunafiev, R.Z. et al. Crystal structure of pseudokopsinine and its salts. J Struct Chem 58, 291–296 (2017). https://doi.org/10.1134/S002247661702010X
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DOI: https://doi.org/10.1134/S002247661702010X