Abstract
A series of fluoro- and hydroxy-substituted thiocarboxyhydrazones, 2-(3-fluorobenzylidene)-Nmethylhydrazinecarbothioamide (1), 2-(2,3-difluorobenzylidene)-N-methylhydrazinecarbothioamide (2), and 2-(2-hydroxybenzylidene)-N-methylhydrazinecarbothioamide (3), are synthesized and characterized by elemental analysis, IR and UV-vis spectra, and single crystal X-ray diffraction. Structures of the three compounds are similar, but with a slight modification due to fluoro substituting groups. The crystal structures of the compounds are stabilized by hydrogen bonds and π...π interactions. The antimicrobial activity of the compounds shows that they are effective against some bacteria.
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Original Russian Text © 2015 Z.-X. Liu.
The text was submitted by the authors in English. Zhurnal Strukturnoi Khimii, Vol. 56, No. 7, pp. 1476-1480, November-December, 2015.
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Liu, ZX. Structures and antimicrobial activity of fluoro- and hydroxy-substituted thiocarboxyhydrazones. J Struct Chem 56, 1420–1425 (2015). https://doi.org/10.1134/S0022476615070276
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DOI: https://doi.org/10.1134/S0022476615070276