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A Study of Rat Myocardial Na/K-ATPase Activity in Experimental Conditions of Prediabetes and Diabetes Mellitus

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REFERENCES

  1. Bugger, H. and Abel, E.D., Molecular mechanisms of diabetic cardiomyopathy, Diabetologia, 2014, vol. 57, no. 4, pp. 660–671.

    Article  CAS  Google Scholar 

  2. Hölscher, M.E., Bode, C., and Bugger, H., Diabetic cardiomyopathy: does the type of diabetes matter? Int. J. Mol. Sci., 2016, vol. 17, no. 12, p. E2136.

    Article  Google Scholar 

  3. Louch, W.E., Sejersted, O.M., and Swift, F., There goes the neighborhood: pathological alterations in T-tubule morphology and consequences for cardiomyocyte Ca2+ handling, J. Biomed. Biotechnol., 2010, p. 503906.

  4. Dobretsov, M., Romanovsky, D., and Stimers, J.R., Early diabetic neuropathy: triggers and mechanisms, World J. Gastroenterol., 2007, vol. 13, pp. 175–191.

    Article  CAS  Google Scholar 

  5. Rosta, K., Tulassay, E., Enzsoly, A., Ronai, K., Szantho, A., Pandics, T., Fekete, A., Mandl, P., and Ver, A., Insulin induced translocation of Na+/K+-ATPase is decreased in the heart of streptozotocin diabetic rats, Acta Pharmacol. Sin., 2009, vol. 30, pp. 1616–1624.

    Article  CAS  Google Scholar 

  6. P-type ATPases: Methods and Protocols, Methods in Molecular Biology, Bublitz, M., Ed., New York, 2016, 1377.

  7. Yefimov, D.A., Mechanism of experimental diabetic cardiomyopathy development, Mezhd. Endokrinol. Zh., 2012, vol. 2(42), pp. 67–69.

  8. Lambert, R., Srodulski, S., Peng, X., Margulies, K.B., Despa, F., and Despa, S., Intracellular Na+ concentration ([Na+]i) is elevated in diabetic hearts due to enhanced Na+-glucose cotransport, J. Am. Heart Assoc., 2015, 4:e002183.

  9. Despa, S., Lingrel, J.B., and Bers, D.M., Na/K-ATPase α2-subunit preferentially affects sarcoplasmic reticulum Ca release in mouse cardiacmyocytes, Cardiovasc. Res., 2012, vol. 95, pp. 480–486.

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ACKNOWLEDGMENTS

This work was implemented using the equipment of the Center for Collective Use at Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences.

Funding

This study was supported by the Russian Foundation for Basic Research (grant no. 19-015-00139).

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Correspondence to O. V. Chistyakova.

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Experiments complied with rules and regulations on conducting research with laboratory animals approved by the Ethics Committee at Sechenov Institute of Evolutionary Physiology and Biochemistry (30.12.2015) and requirements of the European Union Directive of 1986.

This study did not involve human subjects as research objects.

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Chistyakova, O.V., Sukhov, I.B., Dobretsov, M.G. et al. A Study of Rat Myocardial Na/K-ATPase Activity in Experimental Conditions of Prediabetes and Diabetes Mellitus. J Evol Biochem Phys 56, 174–177 (2020). https://doi.org/10.1134/S0022093020020118

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  • DOI: https://doi.org/10.1134/S0022093020020118

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