Skip to main content
SpringerLink
Log in

Effect of ganglioside GM1 on mitochondrial respiration and viability of PC12 cells under oxidative stress

  • Short Communications
  • Published:
Journal of Evolutionary Biochemistry and Physiology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Vassault, A., Lactate dehydrogenase: UV-method with pyruvate and NADH, Methods of Enzymatic Analysis, Bergmeyer, H.U., Ed., Weinheim, Verlag Chemie, 1983, vol. 3, pp. 118–126.

    Google Scholar 

  2. Skulachev, V.P., Mitochondrial physiology and pathology, concepts of programmed death of organelles, cells and organisms, Mol. Asp. Med., 1999, vol. 20, pp. 139–184.

    Article  CAS  Google Scholar 

  3. Lemasters, J.J., Selective mitochondrial autophagy, or mitophagi, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging, Rejuv. Res., 2005, vol. 8, pp. 3–5.

    Article  CAS  Google Scholar 

  4. Duchemin, A.M., Ren, Q., Neff, N.H., and Hadjiconstantinou, M., GM1-induced activation of phosphatidylinositol 3-kinase: involvement of Trk receptors, J. Neurochem., 2008, vol. 104, pp. 1466–1477.

    Article  CAS  PubMed  Google Scholar 

  5. Avrova, N.F., Sokolova, T.V., Vlasova, Y.A., Zakharova, I.O., Furaev, V.V., and Rychkova, M.P., Protective and antioxidative effects of GM1 ganglioside in PC12 cells exposed to hydrogen peroxide are mediated by Trk tyrosine kinase, Neurochem. Res., 2010, vol. 35, pp. 85–98.

    Article  CAS  PubMed  Google Scholar 

  6. Whelan, R.S., Konstantinidis, K., Wei, A.C., Chen, Y., Reyna, D.E., Jha, S., Yang, Y., Calvert, J.W., Lindsten, T., Thompson, C.B., Crow, M.T., Gavathiotis, E., Dorn, G.W., 2nd, O’Rourke, B., and Kitsis, R.N., Bax regulates primary necrosis through mitochondrial dynamics, Proc. Natl. Acad. Sci. USA, 2012, vol. 109, pp. 6566–6571.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia

    I. V. Brailovskaya, T. V. Sokolova & N. F. Avrova

  2. Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia

    A. G. Kobylyanskii

Authors
  1. I. V. Brailovskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. V. Sokolova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. G. Kobylyanskii
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. F. Avrova
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to I. V. Brailovskaya.

Additional information

Original Russian Text © I.V. Brailovskaya, T.V. Sokolova, A.G. Kobylyanskii, N.F. Avrova, 2014, published in Zhurnal Evolyutsionnoi Biokhimii i Fiziologii, 2014, Vol. 50, No. 2, pp. 155–157.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Brailovskaya, I.V., Sokolova, T.V., Kobylyanskii, A.G. et al. Effect of ganglioside GM1 on mitochondrial respiration and viability of PC12 cells under oxidative stress. J Evol Biochem Phys 50, 174–176 (2014). https://doi.org/10.1134/S0022093014020100

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0022093014020100

Keywords

Search

Navigation