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Blood supply as a factor regulating pacemaker activity of the rat uterine horn

Abstract

The effect of ischemia of the uterine artery supplying blood to the main rhythmogenic ovarian zone of the uterine horn in non-pregnant rats was investigated. Parameters of pacemaker activity of the given locus and all the subsequent pacemaker areas up to the cervix were studied under the influence of ischemia. The greatest changes of the amplitude, frequency and burst duration time of spike activities were recorded in the ovarian end of horn. The uterine corpus and cervical end of horn were less affected by ischemia. However, amplitude of the slow-wave oscillations increased by more than one and a half in these conditions. Data obtained allow us to state about presence of certain connection between the ovarian end of horn and uterine cervix. Morphological studies revealed strong vascularization of the upper part of uterine horn.

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Correspondence to K. V. Kazaryan.

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Original Russian Text © K.V. Kazaryan, N.G. Hunanyan, N.N. Melkonyan, 2013, published in Zhurnal Evolyutsionnoi Biokhimii i Fiziologii, 2013, Vol. 49, No. 1, pp. 60–66.

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Kazaryan, K.V., Hunanyan, N.G. & Melkonyan, N.N. Blood supply as a factor regulating pacemaker activity of the rat uterine horn. J Evol Biochem Phys 49, 84–90 (2013). https://doi.org/10.1134/S0022093013010106

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  • DOI: https://doi.org/10.1134/S0022093013010106

Key words

  • uterus
  • uterine horn
  • ovarian part
  • cervical part
  • uterine cervix
  • spike activity
  • slow-wave activity