Abstract
Biomechanical properties of the human skull affect its dynamic tensility (pliability or compliance) at changes of intracranial volume and pressure (ΔV/ΔP). The work substantiates a possibility of noninvasive and dynamic evaluation of cranial compliance by synchronous recording of transcranial dopplerogram of middle cerebral artery and cranial bioimpedance that provides information about pulsative changes of intracranial pressure and volume, respectively, with subsequent computer pattern and phasic analysis of these processes. The characteristic peculiarities of the cranial compliance at rest and during action of functional hemo- and liquorodynamic tests were traced in people of the middle (40–50 years) and elderly (70–85 years) age groups as compared with the young group (20–30 years). A relative decrease of this parameter has been revealed in the middle age group due to an increase of rigidity of skull bones and ligaments, which indicates a decrease of tolerance of the intracranial circulatory system. However, in the group of 70–85 years the compliance parameters rose due to an increase of intracranial liquor volume and activation of liquor circulation inside the craniospinal space, which is a compensatory mechanism for maintenance of the adequate brain circulatory-metabolic activity.
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Original Russian Text © Yu. E. Moskalenko, G. B. Weinstein, P. Halvorson, T. I. Kravchenko, N. A. Ryabchikova, A. Feilding, V. N. Semernya, A. A. Panov, 2008, published in Zhurnal Evolyutsionnoi Biokhimii i Fiziologii, 2008, Vol. 44, No. 5, pp. 513–520.
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Moskalenko, Y.E., Weinstein, G.B., Halvorson, P. et al. Biomechanical properties of human cranium: Age-relayed aspects. J Evol Biochem Phys 44, 605–614 (2008). https://doi.org/10.1134/S0022093008050101
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DOI: https://doi.org/10.1134/S0022093008050101