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Changes of the serotonergic system activity in fish tissues during an increase of water salinity

  • Comparative and Ontogenic Physiology
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Abstract

Changes of environment parameters produce essential effects on the serotonergic system activity in the body tissues. This paper describes study of the serotonergic system activity in various tissues of half-migratory fish—the Caspian roach Rutilus rutilus caspicus and the bream Abramis brama orientalis—caught in the fresh and brackish water. Using the method of indirect solid-phase ELISA test, the serotonergic system activity was assessed by determining in the studied fish tissues of the amount of serotonin-modulating anticonsolidation protein (SMAP) that is in the linear correlation with serotonin level. A significant change of the SMAP level in the Caspian roach and bream brain was found under effect on increased water salinity. Analysis of the SMAP amount in the bream liver did not reveal any differences in the animals caught in the brackish and fresh water. At the same time, in the bream gill there was a small rise of the SMAP content in the fish caught in the brackish water. The revealed in this experiment elevation of the SMAP amount in the Caspian roach and bream brain reflecting a corresponding increase of the serotonergic system activity indicates involvement of adaptive readjustments in the animal body.

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References

  1. Gopkalov, V.G., Serotonin Receptors of the First Type (S1) in Rats with Different Level of Brain Audiogenic Excitation, Biologicheski aktivnye veshchestva i regulyatsiya funktsii mozga (Biologically Active Substances and Brain Function Regulation), Kharkov, 1990, pp. 46–48.

  2. Antitela. Metody (Antibodies. Methods), Katy, D., Ed., vol. 2, Moscow, 1991.

  3. Mekhtiev, A.A., Detection in the Rat Brain of Protein with Anticonsolidation Properties, Byull. Exp. Biol. Med., 2000, vol. 129, no. 8, pp. 147–150.

    Google Scholar 

  4. Gasanov, G.G. and Mekhtiev, A.A., Detection of Serotonin-Modulating Protein Fraction and Study of Its Participation in Organization of the Passive Avoiding Behavior, Byull. Exp. Biol. Med., 1991, vol. 112, no. 7, pp. 5–7.

    CAS  Google Scholar 

  5. Mekhtiev, A.A., Kozyrev, S.A., Nikitin, V.P., and Sherstnev, V.V., Selective Effect of Antibodies to SMP-69 Protein on Activity of Command Neurons of the Protective Behavior in Edible Snails, Sechenov Ross. Fiziol. Zh. RAN, 2003, vol. 89, pp. 389–396.

    CAS  Google Scholar 

  6. Scoups, R., Metody ochistki belkov (Methods of Protein Purification), Moscow, 1985.

  7. Shmalhausen, I.I., Proiskhozhdenie nazemnykh pozvonochnykh (Origin of Terrestrial Vertebrate), Moscow, 1964.

  8. Vladimirov, V.I., About Origin of the Caucasian Trout, Izv. Armyansk. AN, 1944, no. 1, pp. 145–156.

  9. Derzhavin, A.N., A Note about Fish of the Keredge River (North Persia), Izv. Bakinsk. Ikhtiol. Lab., 1929, vol. 2, no. 2, pp. 69–78.

    Google Scholar 

  10. Berg, L.S., Izbr. trudy, tom 4, Ikhtiologiya ((Select-ed Works, vol. 4, Ichthyology), Moscow, Leningrad, 1961.

    Google Scholar 

  11. Sudak, H.S. and Maas, J.W., Behavioral-Neurochemical Correlation in Reactive and Non-Reactive Strains of Rats, Behav. Gen., 1969, N.Y, pp. 471–475.

  12. Ismailova, Kh.Yu., Semenova, N.P., Fast, A.E., Gasanov, G.G., and Gromova, E.A., A Comparative Analysis of Learning and Exploratory Behavior of Rats with Varying Resistance to Stressor Influences and the Level of the Brain Monoamines, Neurosci. Behav. Physiol., 1993, vol. 23, pp. 336–343.

    Article  PubMed  Google Scholar 

  13. Clinckers, R., Smolders, I., Meurs, A., Ebinger, G., and Michotte, Y., Hippocampal Dopamine and Serotonin Elevations as Pharmacodynamic Markers for the Anticonvulsant Efficacy of Oxcarbazepine and 10,11-Dihydro-10-Hydroxycarbamazepine, Neurosci. Lett., 2005, vol. 390, no. 1, pp. 48–53.

    Article  CAS  PubMed  Google Scholar 

  14. Isaac, M., Serotonergic 5-HT2C Receptors as a Potential Therapeutic Target for the Design Antiepileptic Drugs, Curr. Top. Med. Chem., 2005, vol. 5, no. 1, pp. 59–67.

    Article  CAS  PubMed  Google Scholar 

  15. Mekhtiev, A.A., Gaisina, A.A., Palatnikov, G.M., and Kasimov, R.Yu., Serotonin-Modulating Protein Content as a Biomarker of Environmental Pollution, Soil Sedim. Contam.: Intern. J., 2005, vol. 14, no. 2, pp. 115–121.

    Article  CAS  Google Scholar 

  16. de Boeck, G., Nilsson, G.E., Vlaeminck, A., and Blust, R., Central Monoaminergic Responses to Salinity and Temperature Rises in Common Carp, J. Exp. Biol., 1996, vol. 199, pp. 1605–1611.

    PubMed  Google Scholar 

  17. Buznikov, G.A., Neirotransmitteri v embriogeneze (Neurotransmitters in Embryogenesis), Moscow, 1987.

  18. Azmitia, E.C., Modern Views on an Ancient Chemical: Serotonin Effects on Cell Proliferation, Maturation, and Apoptosis, Brain Res. Bull., 2001, vol. 56, pp. 413–424.

    Article  CAS  PubMed  Google Scholar 

  19. Buznikov, G.A., Wayne-Lambert, H., and Lauder, J.M., Serotonin and Serotonin-Like Substances as Regulators of Early Embryogenesis and Morphogenesis, Cell Tiss. Res., 2001, vol. 305, pp. 177–186.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Zoology, Azerbaijan National Academy of Sciences, Baku, Azerbaijan

    N. J. Mustafayev

  2. Karaev Institute of Physiology, Azerbaijan National Academy of Sciences, Baku, Azerbaijan

    A. A. Mekhtiev

Authors
  1. N. J. Mustafayev
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  2. A. A. Mekhtiev
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Original Russian Text © N. J. Mustafayev, A. A. Mekhtiev, 2008, published in Zhurnal Evolyutsionnoi Biokhimii i Fiziologii, 2008, Vol. 44, No. 1, pp. 60–64.

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Mustafayev, N.J., Mekhtiev, A.A. Changes of the serotonergic system activity in fish tissues during an increase of water salinity. J Evol Biochem Phys 44, 69–73 (2008). https://doi.org/10.1134/S0022093008010088

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  • DOI: https://doi.org/10.1134/S0022093008010088

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