Abstract
Among numerous regulatory peptides (RP) it is possible to presumably indicate the relict, evolutionary ancient RP. They combine three features: formation from non-specialized peptides-precursors, a comparatively high resistance to action of proteases in the organism media, and maximal simplicity of their structure. The examples of them are glyprolines—a recently identified RP family, as well as tuftsin. Several other praline-containing RP in terminal sites also seem to belong to the evolutionary ancient RP. The proposed approach to studies on the RP evolution is additional to those used traditionally in this problem.
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Original Russian Text © I. P. Ashmarin and E. P. Karazeeva, 2007, published in Zhurnal Evolyutsionnoi Biokhimii i Fiziologii, 2007, Vol. 43, No. 1, pp. 104–106.
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Ashmarin, I.P., Karazeeva, E.P. Search for evolutionary ancient, relict, regulatory peptides. J Evol Biochem Phys 43, 123–125 (2007). https://doi.org/10.1134/S0022093007010139
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DOI: https://doi.org/10.1134/S0022093007010139