Abstract
Processes of unsteady transcapillary exchange in hemodynamics with allowance for plasma motion in the interstitial space are studied by methods of physical and mathematical modeling. The presence of pulse oscillations of pressure in the network of capillaries is responsible for separation of filtration and re-absorption through capillary walls in space and time. General and specific properties of functioning of the arteriole, intermediate, and venule segments of the capillary network in exchange properties are demonstrated. Pressure oscillations are found to enhance transcapillary exchange.
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References
B. Folkov and E. Nil, Blood Circulation [in Russian], Meditsina, Moscow (1976).
A. M. Chernukh, P. P. Aleksandrov, and O. V. Alekseev, Microcirculation [in Russian], Meditsina, Moscow (1975).
V. I. Kozlov, E. P. Melman, E. M. Neiko, and B. V. Shutka, Histophysiology of Capillaries [in Russian], Nauka, St. Petersburg (1994).
S. N. Bagaev, V. N. Zakharov, V. A. Orlov, et al., “Investigation of physical mechanisms of blood microcirculation and transcapillary exchange by a phase-sensitive laser method,” Ros. Zh. Biomekh., 10, No. 3, 22–40 (2006).
A. G. Kamkin and A. A. Kamenskii (eds.), Basic and Clinical Physiology [in Russian], Akademiya, Moscow (2004).
S. N. Bagaev, V. N. Zakharov, V. A. Orlov, et al., “Regulation of transcapillary exchange by pulse pressure of blood,” Ross. Zh. Biomekh., 12, No. 3, 7–14 (2008).
C. G. Caro, T. J. Pedley, R. C. Schroter, and W. A. Seed, The Mechanics of the Circulation, Oxford University Press, Oxford (1978).
N. S. Shabrykina, “Mathematical modeling of microcirculation processes,” Ros. Zh. Biomekh., 9, No. 3, 70–88 (2005).
I. E. Idel’chik, Handbook on Hydrodynamic Resistances [in Russian], Mashinostroenie, Moscow (1992).
M. I. Zhilyaev and T. A. Pupykina, “Modification of the central difference scheme for calculating two-dimensional inviscid flows in force fields,” Chisl. Metody Mekh. Sploshnoi Sredy, 14, No. 3, 65–75 (1983).
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Translated from Prikladnaya Mekhanika i Tekhnicheskaya Fizika, Vol. 52, No. 2, pp. 92–102, March–April, 2011.
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Khmel’, T.A., Fedorov, A.V., Fomin, V.M. et al. Modeling of blood microcirculation processes with allowance for pulse pressure oscillations. J Appl Mech Tech Phy 52, 234–242 (2011). https://doi.org/10.1134/S0021894411020118
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DOI: https://doi.org/10.1134/S0021894411020118