Production of 149Tb in Nuclear Reactions Induced by Alpha-particles
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149Tb is the only known isotope decaying both by emission of alpha-particles and positrons. This unique feature makes it possible to unite in one radionuclide two main tools of nuclear medicine: cancer therapy by a-particles and diagnostics using positron emission tomography. The existing ways of production of 149Tb are far from being practical. In this paper a simulation of the excitation functions of the nuclear reactions 151Eu(α, 6n)149Tb and 153E(α, 8n)149Tb was carried out. The cross-sections in the maxima (approximately 65 and 80MeV correspondingly) are predicted to reach one barn, and the targets could be made from natural Europium. Thus these reactions can serve as a basis of a new promising technology for production of 149Tb isotope for use in a modern field of nuclear medicine, theranostics.
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