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Production of 149Tb in Nuclear Reactions Induced by Alpha-particles

  • N. N. Il’inskaya
  • T. Yu. Malamut
  • A. A. Ogloblin
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Abstract

149Tb is the only known isotope decaying both by emission of alpha-particles and positrons. This unique feature makes it possible to unite in one radionuclide two main tools of nuclear medicine: cancer therapy by a-particles and diagnostics using positron emission tomography. The existing ways of production of 149Tb are far from being practical. In this paper a simulation of the excitation functions of the nuclear reactions 151Eu(α, 6n)149Tb and 153E(α, 8n)149Tb was carried out. The cross-sections in the maxima (approximately 65 and 80MeV correspondingly) are predicted to reach one barn, and the targets could be made from natural Europium. Thus these reactions can serve as a basis of a new promising technology for production of 149Tb isotope for use in a modern field of nuclear medicine, theranostics.

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References

  1. 1.
    B. J. Allen and N. Blagojevic, Nucl. Med. Commun. 17 40 (1996).CrossRefGoogle Scholar
  2. 2.
    C. Müller, K. Zhernosekov, U. Köster, K. Johnston, H. Dorrer, A. Hohn, N. T. van der Walt, A. Türler, and R. Schibli, J. Nucl. Med. 53 1951 (2012).CrossRefGoogle Scholar
  3. 3.
    V. A. Zagryadskiy, S. T. Latushkin, T. Y. Malamut, V. I. Novikov, A. A. Ogloblin, V. N. Luneev, and D. Y. Chuvilin, Atomic energy 123(1), 45 (2017).Google Scholar
  4. 4.
    C. Müller, J. Reber, S. Haller, H. Dorrer, U. Köster, K. Johnston, K. Zhernosekov, A. Türler, and R. Schibli, Pharmaceuticals 7 353 (2014).CrossRefGoogle Scholar
  5. 5.
    A. Koning, S. Hilaire, and S. Goliery, TALYS-1.8 A Nuclear Reaction Progr, User Manual, The Netherlands (2015).Google Scholar
  6. 6.
    S. Mukherjee, B. Bindi Kumar, M. H. Rashid, and S. N. Chintalapudi, Phys. Rev. C 55(5), 2556 (1997).ADSCrossRefGoogle Scholar
  7. 7.
    J. Lange and H. Munzel, Preprint Kernforshungszentrum KFK 767, Karlsruhe (1968).Google Scholar
  8. 8.
    G. J. Beyer, J. J. Comor, M. Dakovic, D. Soloviev, C. Tamburella, E. Hagebo, B. Allan, S. N. Dmitriev, N. G. Zaitseva, G. Y. Starodub, L. G. Molokanova, S. Vranjes, M. Miederer, and ISOLDE Collaboration, Radiochim. Acta. 90 247 (2002).CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Inc. 2018

Authors and Affiliations

  • N. N. Il’inskaya
    • 1
  • T. Yu. Malamut
    • 1
  • A. A. Ogloblin
    • 1
  1. 1.National Research Center “Kurchatov Institute”MoscowRussia

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