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Fractal globule as a molecular machine

  • Biophysics
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Abstract

A fractal (crumpled) polymer globule, which is an unusual equilibrium state of a condensed unknotted macromolecule that is experimentally found in the DNA folding in human chromosomes, has been formed through the hierarchical collapse of a polymer chain. The relaxation dynamics of the elastic network constructed through the contact matrix of the fractal globule has been studied. It has been found that the fractal globule in its dynamic properties is similar to a molecular machine.

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Authors and Affiliations

  1. Semenov Institute of Chemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119991, Russia

    V. A. Avetisov & D. A. Meshkov

  2. National Research University Higher School of Economics, ul. Malaya Ordynka 17, Moscow, 109028, Russia

    V. A. Avetisov

  3. Moscow State University, Moscow, 119991, Russia

    V. A. Ivanov

  4. Lebedev Physical Institute, Russian Academy of Sciences, Leninskii pr. 53, Moscow, 119991, Russia

    S. K. Nechaev

  5. CNRS, LPMS, UMR8626, Université Paris-Sud, 91405, Orsay, France

    S. K. Nechaev

Authors
  1. V. A. Avetisov
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  2. V. A. Ivanov
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  3. D. A. Meshkov
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  4. S. K. Nechaev
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Corresponding author

Correspondence to V. A. Avetisov.

Additional information

Original Russian Text © V.A. Avetisov, V.A. Ivanov, D.A. Meshkov, S.K. Nechaev, 2013, published in Pis’ma v Zhurnal Eksperimental’noi i Teoreticheskoi Fiziki, 2013, Vol. 98, No. 4, pp. 270–274.

See supplemental materials at http://www.jetpletters.ac.ru/cgi-bin/front/supplemental/ru-98-4-p270/10.

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Avetisov, V.A., Ivanov, V.A., Meshkov, D.A. et al. Fractal globule as a molecular machine. Jetp Lett. 98, 242–246 (2013). https://doi.org/10.1134/S0021364013170025

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  • DOI: https://doi.org/10.1134/S0021364013170025

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