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Stability of bioactive hydroxyapatite films on titanium substrates in physiological buffer solutions

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Abstract

Hydroxyapatite/titanium (HA/Ti) structures heat-treated and then incubated in CaCl2 (3 mM Ca2+) and KH2PO4 + Na2HPO4 (20 mM; pH 6, 7, 8) solutions have been characterized by X-ray diffraction, X-ray microanalysis, scanning electron microscopy, and pX measurements. The insoluble phases CaTiO3 and CaTi4O9 have been identified. After prolonged incubation (96 h), the heat-treated structures were found to be biologically resistant. Thermostating the structures in the physiological buffer solutions studied does not rupture the bioactive film, and the HA/Ti structure is stable in such solutions.

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Authors and Affiliations

  1. Voronezh State University, Universitetskaya pl. 1, Voronezh, 394006, Russia

    A. Yu. Berezhnaya, I. Ya. Mittova & A. V. Kostyuchenko

  2. Burdenko State Medical Academy, Studencheskaya ul. 10, Voronezh, 394036, Russia

    V. O. Mittova

Authors
  1. A. Yu. Berezhnaya
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  2. V. O. Mittova
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  3. I. Ya. Mittova
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  4. A. V. Kostyuchenko
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Correspondence to A. Yu. Berezhnaya.

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Original Russian Text © A.Yu. Berezhnaya, V.O. Mittova, I.Ya. Mittova, A.V. Kostyuchenko, 2012, published in Neorganicheskie Materialy, 2012, Vol. 48, No. 11, pp. 1274–1279.

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Berezhnaya, A.Y., Mittova, V.O., Mittova, I.Y. et al. Stability of bioactive hydroxyapatite films on titanium substrates in physiological buffer solutions. Inorg Mater 48, 1141–1146 (2012). https://doi.org/10.1134/S0020168512110015

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  • DOI: https://doi.org/10.1134/S0020168512110015

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