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Effect of the concentration of carbonate groups in a carbonate hydroxyapatite ceramic on its in vivo behavior

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Abstract

Carbonate-substituted hydroxyapatites containing up to 9 wt % of carbonate groups were synthesized and fabricated in the form of porous granules with a view to developing materials for use in bone tissue repairs. The use of sintering additives forming a liquid phase allowed the granule sintering temperature to be reduced by 400–450°C. It was found that the carbonate groups enter into the structure of the ceramic by a mixed AB-type substitution; the microstructure of the granules depends substantially on the concentration of the carbonate groups; introduction of 6 wt % of carbonate groups into apatite ensures high biological properties of the granules in experiments in vivo.

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Authors and Affiliations

  1. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Moscow, Russia

    V. S. Komlev, I. V. Fadeeva, V. V. Smirnov & S. M. Barinov

  2. Central Scientific Research Institute of Stomatology and Maxillofacial Surgery, Rosmedtekhnologii, Moscow, Russia

    A. N. Gurin & N. A. Gurin

  3. Moscow State University, Moscow, Russia

    E. S. Kovaleva

Authors
  1. V. S. Komlev
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  2. I. V. Fadeeva
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  3. A. N. Gurin
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  4. E. S. Kovaleva
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  5. V. V. Smirnov
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  6. N. A. Gurin
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  7. S. M. Barinov
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Corresponding author

Correspondence to V. S. Komlev.

Additional information

Original Russian Text © V.S. Komlev, I.V. Fadeeva, A.N. Gurin, E.S. Kovaleva, V.V. Smirnov, N.A. Gurin, S.M. Barinov, 2009, published in Neorganicheskie Materialy, 2009, Vol. 45, No. 3, pp. 373–378.

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Komlev, V.S., Fadeeva, I.V., Gurin, A.N. et al. Effect of the concentration of carbonate groups in a carbonate hydroxyapatite ceramic on its in vivo behavior. Inorg Mater 45, 329–334 (2009). https://doi.org/10.1134/S0020168509030194

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  • DOI: https://doi.org/10.1134/S0020168509030194

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