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Photosensitizing Properties of a Boron Difluoride Beta-Diketonate Derivative

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Abstract

The photosensitizing ability of a boron difluoride beta-diketonate derivative has been studied. The spectral and luminescent properties of the dye and the spectral-kinetic characteristics of its triplet state have been established. The quantum efficiency of singlet oxygen formation has been determined. The in vitro photosensitizing activity of the dye against tumor cells of colon adenocarcinoma was demonstrated, and the values of dark and photoinduced cytotoxicity were obtained.

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ACKNOWLEDGMENTS

The studies were carried out using the equipment of the Shared-Use Center “New Materials and Technologies” at the Emanuel Institute of Biochemical Physics.

Funding

The study was supported by the Russian Science Foundation, project no. 23-23-00461. The experiments on cells were supported within the framework of the State program of the Russian Federation for the Emanuel Institute of Biochemical Physics, project no. 122041400114-2.

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Correspondence to A. E. Egorov.

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Translated by S. Zatonsky

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Egorov, A.E., Mirochnik, A.G., Fedorenko, E.V. et al. Photosensitizing Properties of a Boron Difluoride Beta-Diketonate Derivative. High Energy Chem 58, 103–106 (2024). https://doi.org/10.1134/S0018143924010053

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