Abstract
Conformational changes in polyampholyte polypeptides adsorbed on the surface of an oblate metal nanospheroid with a periodic change in time of its polarity along the axis of rotation have been studied using the molecular dynamics method. The radial distributions of polypeptide atoms, as well as the distributions of the linear density of polypeptide atoms along the nanospheroid rotation axis, are constructed. The obtained conformational structures of polyampholytes were compared in the presence and in the absence of sodium and chlorine ions in water. At low temperatures, the formation of a narrow macromolecular ring around the nanospheroid near the equator was observed; the ring swelled with an increase in the amplitude of an external alternating electric field; and polyampholyte desorption occurred with a further increase in the amplitude. At high temperatures, periodic changes in the conformational structure of adsorbed polyampholytic polypeptides were observed on the surface of the oblate metal nanospheroid with the frequency of an external polarizing alternating field.
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REFERENCES
Fuller, M.A. and Koper, I., Nano Converg., 2019, vol. 6, p. 11.
Szekeres, G.P., Montes-Bayon, M., Bettmer, J., and Kneipp, J., Anal. Chem., 2020, vol. 92, p. 8553.
Khlebtsov, B.N., Khanadeev, V.A., Burov, A.M., Le Ru, E.C., and Khlebtsov, N.G., J. Phys. Chem. C, 2020, vol. 124, p. 10647.
Xu, X., Liu, Y., Yang, Y., Wu, J., Cao, M., and Sun, L., Colloids Surf., A, 2022, vol. 640, p. 128491.
Farcas, A., Janosi, L., and Astilean, S., Comput. Theor. Chem., 2022, vol. 1209, p. 113581.
Guo, Q., Ding, L., Li, Y., Xiong, S., Fang, H., Li, X., Nie, L., Xiong, Y., and Huang, X., Sens. Actuators, B, 2022, vol. 364, p. 131872.
Ma, F., Wang, Q., Xu, Q., and Zhang, C., Anal. Chem., 2021, vol. 93, p. 15124.
Wu, Y., Wang, X., Wen, X., Zhu, J., Bai, X., Jia, T., Yang, H., Zhang, L., and Qi, Y., Phys. Lett. A, 2020, vol. 384, p. 126544.
Mazzotta, F., Johnson, T.W., Dahlin, A.B., Shaver, J., Oh, S., and Höök, F., ACS Photonics, 2015, vol. 2, p. 256.
Klimov, V.V., Ducloy, M., and Letokhov, V.S., Chem. Phys. Lett., 2002, vol. 358, p. 192.
Liaw, J., Wu, H., Huang, C., and Kuo, M., Nanoscale Res. Lett., 2016, vol. 11, no. 26.
Chandra, S., Doran, J., and McCormack, S.J., J. Colloid Interface Sci., 2015, vol. 459, p. 218.
Piralaee, M., Asgari, A., and Siahpoush, V., Optik, 2018, vol. 172, p. 1064.
Chen, Y., Cruz-Chu, E.R., Woodard, J., Gartia, M.R., Schulten, K., and Liu, L., ACS Nano, 2012, vol. 6, p. 8847.
Radhakrishnan, K. and Singh, S.P., Macromolecules, 2021, vol. 54, p. 7998.
Netz, R.R., J. Phys. Chem. B, 2003, vol. 107, p. 8208.
Mahinthichaichan, P., Tsai, C., Payne, G.F., and Shen, J., ACS Omega, 2020, vol. 5, p. 12016.
Qi, S., Lin, M., Qi, P., Shi, J., Song, G., Fan, W., Sui, K., and Gao, C., Chem. Eng. J., 2022, vol. 444, p. 136541.
Kruchinin, N.Yu. and Kucherenko, M.G., Biophysics, 2020, vol. 65, no. 2, p. 186.
Kruchinin, N.Yu. and Kucherenko, M.G., Colloid J., 2021, vol. 83, no. 1, p. 79.
Kruchinin, N.Yu., Kucherenko, M.G., and Neyasov, P.P., Russ. J. Phys. Chem. A, 2021, vol. 95, no. 2, p. 362.
Kruchinin, N.Yu. and Kucherenko, M.G., Surf. Interfaces, 2021, vol. 27, p. 101517.
Kruchinin, N.Yu. and Kucherenko, M.G., Colloid J., 2021, vol. 83, no. 5, p. 591.
Kruchinin, N.Yu. and Kucherenko, M.G., Russ. J. Phys. Chem. A, 2022, vol. 96, no. 3, p. 622.
Kruchinin, N.Yu. and Kucherenko, M.G., Colloid J., 2020, vol. 82, no. 4, p. 392.
Kruchinin, N.Yu. and Kucherenko, M.G., Eurasian Phys. Tech. J., 2021, vol. 18, no. 1, p. 16.
Kruchinin, N.Yu., Colloid J., 2021, vol. 83, no. 3, p. 326.
Kruchinin, N.Yu. and Kucherenko, M.G., High Energy Chem., 2021, vol. 55, no. 6, p. 442.
Grosberg A.Yu. and Khokhlov, A.P., Statisticheskaya fizika makromolekul (Statistical Physics of Macromolecules), Moscow: Nauka, 1989.
Landau, L.D. and Lifshits, E.M., Course of Theoretical Physics, vol. 8: Electrodynamics of Continuous Media, Amsterdam: Elsevier, 1984, 2nd ed.
Kruchinin, N.Yu. and Kucherenko, M.G., Colloid J., 2022, vol. 84, no. 2, p. 169.
Phillips, J.C., Braun, R., Wang, W., Gumbart, J., Tajkhorshid, E., Villa, E., Chipot, C., Skeel, R.D., Kale, L., and Schulten, K., J. Comput. Chem., 2005, vol. 26, p. 1781.
Kerell, A.D., Jr., MacBashford, D., Bellott, M., Dunbrack, R.L., Jr., Evanseck, J.D., Field, M.J., Fischer, S., Gao, J., Guo, H., Ha, S., Joseph-McCarthy, D., Kuchnir, L., Kuczera, K., Lau, F.T.K., Mattos, C., Michnick, S., Ngo, T., Nguyen, D.T., Prodhom, B., Reiher W.E., III, Roux, B., Schlenkrich, M., Smith, J.C., Stote, R., Straub, J., Watanabe, M., Wiorkiewicz-Kuczera, J., Yin, D., and Karplus, M., J. Phys. Chem. B, 1998, vol. 102, p. 3586.
Huang, J., Rauscher, S., Nawrocki, G., Ran, T., Feig, M., de Groot, B.L., Grubmüller, H., and Mackerell, A.D., Jr., Nat. Methods, 2016, vol. 14, p. 71.
Heinz, H., Vaia, R.A., Farmer, B.L., and Naik, R.R., J. Phys. Chem. C, 2008, vol. 112, p. 17281.
Walsh, T.R., Acc. Chem. Res., 2017, vol. 50, p. 1617.
Bellucci, L. and Corni, S., J. Phys. Chem. C, 2014, vol. 118, p. 11357.
Cannon, D.A., Ashkenasy, N., and Tuttle, T., J. Phys. Chem. Lett., 2015, vol. 6, p. 3944.
Darden, T., York, D., and Pedersen, L., J. Chem. Phys., 1993, vol. 98, p. 10089.
Jorgensen, W.L., Chandrasekhar, J., Madura, J.D., Impey, R.W., and Klein, M.L., J. Chem. Phys., 1983, vol. 79, p. 926.
Humphrey, W., Dalke, A., and Schulten, K., J. Mol. Graph., 1996, vol. 14, p. 33.
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This study was supported by the Ministry of Science and Higher Education of the Russian Federation, project no. FSGU-2020-0003.
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Translated by S. Zatonsky
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Kruchinin, N.Y., Kucherenko, M.G. Conformational Changes in Polyampholyte Macrochains on the Surface of an Oblate Metallic Nanospheroid in Alternating Electric Field. High Energy Chem 56, 499–510 (2022). https://doi.org/10.1134/S0018143922060108
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DOI: https://doi.org/10.1134/S0018143922060108