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A Spectral-Luminescence Study of Biologically Active 2-Amino-1,3-Thiazoles Containing a Diterpene Fragment in Acetonitrile Solutions

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Abstract

A spectral-luminescence study of a number of 2-amino-1,3-thiazoles containing a diterpene fragment has been carried out. The test compounds were prepared based on the chemical conversion of maleopimaric acid; they exhibit a wide range of biological activities: antitumor, antimicrobial, and antioxidant ones. Their UV spectral and fluorescence characteristics and the quantum yields of luminescence in acetonitrile solutions have been determined. The rule of mirror symmetry in the absorption and fluorescence spectra of the obtained compounds has been found to be violated.

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Funding

The spectral-luminescence measurements were performed using the equipment of the Chemistry and Agidel Centers for Shared Use at the Ufa Institute of Chemistry, Russian Academy of Sciences. This work was carried out at the Ufa Institute of Chemistry, Russian Academy of Sciences within the framework of state contracts AAAA-A20-120012090030-6 (serial no. 0246-2018-0018) and AAAA-A20-120012090026-9 (serial nos. 0246-2018-0023 and 0246-2019-0027).

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Correspondence to S. S. Ostakhov.

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Translated by V. Makhlyarchuk

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Ostakhov, S.S., Sultanova, R.M., Masyagutova, G.A. et al. A Spectral-Luminescence Study of Biologically Active 2-Amino-1,3-Thiazoles Containing a Diterpene Fragment in Acetonitrile Solutions. High Energy Chem 54, 241–245 (2020). https://doi.org/10.1134/S0018143920040104

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  • DOI: https://doi.org/10.1134/S0018143920040104

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