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Photochemical transformations of sphingosine and serinol in aqueous and ethanol solutions

Abstract

It has been established that the main products of the direct photolysis of C15-sphingosine and serinol are 2-tridecenal and glycolaldehyde, which are formed as a result of C–C bond cleavage in the parent compounds. It has been shown that the addition of hydrogen peroxide and acetone to the test solutions extended the range of the photolysis products due to the occurrence of deamination processes. The set of the experimental data has made it possible to propose mechanisms for the photochemical reactions of C15- sphingosine and serinol fragmentation, which occur through the steps of the formation of N- and C-centered radicals.

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References

  1. Ravanat, J.L., Douki, T., and Cadet, J., J. Photochem. Photobiol. B, 2001, vol. 63, p. 88.

    Article  CAS  Google Scholar 

  2. Parkin, D.M., Pisani, P., and Ferlay, J., Int. J. Cancer, 1999, vol. 80, p. 827.

    Article  CAS  Google Scholar 

  3. Dwivedi, A.H. and Pillai, S.G., IJATE, 2014, vol. 2, p. 2348.

    Google Scholar 

  4. Mandal, T.K. and Chatterjee, S.N., Radiat. Res., 1980, vol. 83, no. 2, p. 290.

    Article  CAS  Google Scholar 

  5. Girotti, A.W., J. Photochem. Photobiol. B, 2001, vol. 63, p. 103.

    Article  CAS  Google Scholar 

  6. Holleran, W.M., Takagi, Y., and Uchida, Y., FEBS Lett., 2006, vol. 580, no. 23, p. 5456.

    Article  CAS  Google Scholar 

  7. Borodzicz, S., Rudnicka, L., Mirowska-Guzel, D., and Cudnoch-Jedrzejewska, A., Lipids Health Dis., 2016, vol. 15, p. 13.

    Article  Google Scholar 

  8. Lisovskaya, A.G., Sosnovskaya, A.A., Shadyro, O.I., Kisel’, M.A., and Nikolaevich, V.A., High Energy Chem., 2009, vol. 43, no. 6, p. 440.

    Article  CAS  Google Scholar 

  9. Lisovskaya, A.G., Sladkova, A.A., Sosnovskaya, A.A., and Shadyro, O.I., High Energy Chem., 2012, vol. 46, no. 4, p. 241.

    Article  CAS  Google Scholar 

  10. Lisovskaya, A.G. and Edimecheva, I.P., Radiat. Phys. Chem., 2014, vol. 96, p. 229.

    Article  Google Scholar 

  11. Lisovskaya, A.G., Shadyro, O.I., and Edimecheva, I.P., Photochem. Photobiol., 2012, vol. 88, p. 899.

    Article  CAS  Google Scholar 

  12. Shadyro, O., Lisovskaya, A., Semenkova, G., Edimecheva, I., and Amaegberi, N., Lipid Insights, 2015, vol. 8, p. 1.

    Google Scholar 

  13. Kumar, A., Byun, H.-S., Bittman, R., and Saba, J., Cell. Signal, 2011, vol. 23, p. 1144.

    Article  CAS  Google Scholar 

  14. Calvert, J.G. and Pitts, J.N., Photochemistry, New York: Wiley, 1966.

    Google Scholar 

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Correspondence to A. G. Lisovskaya.

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Original Russian Text © A.G. Lisovskaya, K.O. Procenko, O.I. Shadyro, 2017, published in Khimiya Vysokikh Energii, 2017, Vol. 51, No. 5, pp. 337–342.

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Lisovskaya, A.G., Procenko, K.O. & Shadyro, O.I. Photochemical transformations of sphingosine and serinol in aqueous and ethanol solutions. High Energy Chem 51, 321–326 (2017). https://doi.org/10.1134/S0018143917050071

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  • DOI: https://doi.org/10.1134/S0018143917050071

Keywords

  • sphingolipids
  • photolysis
  • sensitizer
  • degradation
  • radicals