Abstract
Reproduction of endangered species in captivity is an urgent problem for the conservation and restoration of biodiversity. For mammals, including felids, assessing and monitoring of pregnancy progression is fundamental for successful breeding. For the first time, changes in the concentrations of serum amyloid A (SAA), the main protein of the acute phase of inflammation in felines, were assessed during pregnancy in a domestic cat. It was found that changes in SAA concentrations in pregnant females are consistent: an increase to the middle of pregnancy (day 30) and a decrease to day 60. After parturition, the SAA concentrations in the blood of domestic cats increase. The litter size significantly affected the dynamic of SAA concentrations during the experiment, in particular, after parturition, the increase in its level was significantly higher in the females that gave birth to larger litters (from four to seven kittens).
This is a preview of subscription content, log in via an institution to check access.
REFERENCES
Kitchener, A.C., Breitenmoser-Würsten, C., Eizirik E., et al., Cat Newsk, 2017, no. 11, pp. 1–80.
Dinerstein, E., Loucks, C., Wikramanayake, E., et al., BioScience, 2007, vol. 57, no. 6, pp. 508–514.
Amstislavsky, S., Brusentsev, E., Kizilova, E., et al., Reprod. Domest. Anim., 2018, vol. 53, no. 5, pp. 1219–1226.
Guardini, G., Bowen, J., Mariti, C., et al., Animals, 2017, vol. 7, no. 93.
Wielebnowski, N.C., Fletchall, N., Carlstead, K., et al., Zoo Biol., 2002, vol. 21, pp. 77–98.
Erofeeva, M.N., Alekseeva, G.S., Kim, M.D., et al., Animals, 2022, vol. 12, no. 2, p. 165.
Jewgenow, K., Goritz, F., Neubauer, K., et al., J. Eur. Wildl. Res., 2006, vol. 52, pp. 34–38.
Naidenko, S., Erofeeva, M., Goeritz, F., et al., Acta Zool. Sin., 2007, vol. 53, pp. 408–416.
Alekseeva, G.S., Loshchagina, J.A., Erofeeva, M.N., et al., Animals, 2020, vol. 10, p. 903.
Jain, S., Gautam, V., and Naseem, S., J. Pharm. BioAllied Sci., 2011, vol. 3, no. 1, pp. 118–127.
Ulutas, P.A., Musal, B., Kiral, F., et al., Res. Vet. Sci., 2008, vol. 86, no. 3, pp. 373–376.
Heinrich, S.K., Hofer, H., Courtiol, A., et al., Sci. Rep., 2017, vol. 7, no. 1, pp. 1–11.
He, R., Shepard, L.W., Chen, J., et al., J. Immunol., 2006, vol. 177, no. 6, pp. 4072–4079.
Chavan, A.R., Griffith, O.W., Stadtmauer, D.J., et al., Mol. Biol. Evol., 2020, vol. 38, no. 3, pp. 1060–1074.
Prescott, C.W., Aust. Vet. J., 1973, vol. 49, pp. 126–129.
Funding
The work was supported by the Russian Science Foundation (project no. 18-14-00200).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest. The authors declare that they have no conflicts of interest.
Statement on the welfare of animals. The study was approved by the Commission on Bioethics of the Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences (no. 21 dated April 21, 2018).
Additional information
Translated by M. Batrukova
Rights and permissions
About this article
Cite this article
Naidenko, S.V., Alekseeva, G.S., Klyuchnikova, P.S. et al. Changes in Serum Amyloid A Level in Domestic Cats during Pregnancy. Dokl Biol Sci 507, 269–271 (2022). https://doi.org/10.1134/S0012496622060138
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0012496622060138