Skip to main content
SpringerLink
Log in

Influence of Cranial Irradiation with High-Energy Protons on the Visuomotor Behavior in Monkeys

  • PHYSIOLOGY
  • Published:
Doklady Biological Sciences Aims and scope Submit manuscript

Abstract

The visually driven instrumental conditioning of a single monkey (Macaca mulatta) was conducted after single-dose cranial irradiation with high-energy protons. The monkey executed saccades toward the visual stimuli and then responded by manually pressing right or left lever for stimuli in right or left half-field, respectively. The percentage of correct responses with dominant right hand exceeded the percentage of such responses with left hand and temporarily decreased two months after irradiation. A month later, the percentage of correct right-hand responses returned to the level before irradiation. No significant dynamic was found for changes in percentage of correct left-hand responses. The proton irradiation effect on right-hand responses suggests possible short-term disturbances in the eye-hand coordination for right handedness while the visual perception remains unaffected.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.

Similar content being viewed by others

REFERENCES

  1. Bondar', I.V., Vasil’eva, L.N., Tereshchenko, L.V., et al., Zh. Vysh. Nervn. Deyat., 2018, vol. 68, no. 4, pp. 459–476.

    Google Scholar 

  2. Grigor'ev, A.I., Krasavin, E.A., and Ostrovskii, M.A., Ros. Fiziol. Zh. im. I.M. Sechenova, 2013, vol. 99, no. 3, pp. 273–280.

    CAS  Google Scholar 

  3. Egorov, E.A. and Romanova, T.B., in Oftal’mologiya. Natsional’noe rukovodstvo (Ophthalmology: National Guidelines), Avetisov, S.E., Egorov, E.A., Mosheto-va, L.K., et al., Eds., Moscow: GEOTAR-Media, ch. 11, pp. 91–103.

  4. Tereshchenko, L.V., Molchanov, S.A., Kolesnikova, O.V., et al., Zh. Vysh. Nervn. Deyat., 2012, vol. 62, no. 4, pp. 431–439.

    CAS  Google Scholar 

  5. Chancellor, J.C., Blue, R.S., Cengel, K.A., et al., NPJ Microgravity, 2018, vol. 4, a8.

    Article  Google Scholar 

  6. Cucinotta, F., Alp, M., Sulzman, F., et al., Life Sci. Space Res., 2014, vol. 2, pp. 54–69.

    Article  Google Scholar 

  7. Hopkins, W.D., Washburn, D.A., and Rumbaugh, D.M., J. Comp. Psychol., 1989, vol. 103, no. 1, pp. 91–94.

    Article  CAS  Google Scholar 

  8. Nelson, G.A., Rad. Res., 2016, vol. 185, no. 4, pp. 349–358.

    Article  CAS  Google Scholar 

Download references

Funding

The study was carried out with the financial support of the Russian Foundation for Basic Research (grant nos. 17-29-01027 ofi_m, 17-29-01028 ofi_m).

Author information

Authors and Affiliations

  1. Biological Faculty, Moscow State University, Moscow, Russia

    A. V. Latanov, L. V. Tereschenko & M. A. Ostrovsky

  2. Emanuel Institute for Biochemical Physics, Russian Academy of Sciences, Moscow, Russia

    M. A. Ostrovsky

Authors
  1. A. V. Latanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. V. Tereschenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. A. Ostrovsky
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. V. Latanov.

Ethics declarations

Conflict of interests. The authors declare that they have no conflict of interest.

Statement on the welfare of animals. All manipulations with the animal were performed in accordance with the requirements of the Directive of the European Parliament and the Council of the European Union Council of the European Community (2010/63 / EU) on the use of animals for experimental research.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Latanov, A.V., Tereschenko, L.V. & Ostrovsky, M.A. Influence of Cranial Irradiation with High-Energy Protons on the Visuomotor Behavior in Monkeys. Dokl Biol Sci 487, 95–97 (2019). https://doi.org/10.1134/S0012496619040069

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0012496619040069

Search

Navigation