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Effect of polypeptides from sea anemone Heteractis crispa on the rodent blood pressure, heart rate, and hemostasis

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Abstract

АРНС1–3 peptides, modulators of TRPV1 receptors, have been administered to SD rats to study their influence on the animal hemostatic system, heart rate, and blood pressure. None of АЗРС1–3 polypeptides have any effect on the hemostatic system. Both АРНС1 and АРНС2 polypeptides increased significantly the heart rate, but they did not affect blood pressure, which was probably caused by an ability of these polypeptides to modify animal thermoregulation.

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Authors and Affiliations

  1. Pushchino Branch, Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino, Moscow oblast, Russia

    L. A. Skobtsova, I. A. Dyachenko & A. N. Murashev

  2. Shemyakm–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia

    Ya. A. Andreev, Yu. A. Logashina & E. V. Grishin

  3. Pushchino State Institute of Natural Sciences, Pushchino, Moscow oblast, Russia

    L. A. Skobtsova, I. A. Dyachenko & A. N. Murashev

Authors
  1. L. A. Skobtsova
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  2. I. A. Dyachenko
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  3. Ya. A. Andreev
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  4. Yu. A. Logashina
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  5. A. N. Murashev
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  6. E. V. Grishin
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Corresponding author

Correspondence to I. A. Dyachenko.

Additional information

Original Russian Text © L.A. Skobtsova, I.A. Dyachenko, Ya.A. Andreev, Yu.A. Logashina, A.N. Murashev, E.V. Grishin, 2016, published in Doklady Akademii Nauk, 2016, Vol. 470, No. 2, pp. 239–241.

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Skobtsova, L.A., Dyachenko, I.A., Andreev, Y.A. et al. Effect of polypeptides from sea anemone Heteractis crispa on the rodent blood pressure, heart rate, and hemostasis. Dokl Biol Sci 470, 228–230 (2016). https://doi.org/10.1134/S0012496616050069

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  • DOI: https://doi.org/10.1134/S0012496616050069

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