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Contribution of Nuclear Membrane Phospholipids to the Formation of Electrokinetic Potential

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Abstract

The electrokinetic potential of isolated cell nuclei obtained from wheat seedlings irradiated with nonionizing electromagnetic radiation of extremely high frequencies has been studied. Electrokinetic potential is an important factor in many biological processes and, perhaps, plays an important role in the formation of the response of biological organisms to electromagnetic waves. An increase in the absolute values of the electrokinetic potential of isolated cell nuclei of wheat seedlings from –7.7 to –131.6 mV in the electric field gradient under the influence of electromagnetic radiation of extremely high frequencies, in the frequency range of 46.0–50.3 GHz, was shown. Unidirectional changes in the electrokinetic potential under the influence of such radiation have been revealed; it was explained by an increase in the potential difference between the nuclear membrane and the nuclear matrix. It was also shown that there were sharp differences between the electrokinetic potential of isolated cell nuclei treated with electromagnetic radiation of extremely high frequencies under in vivo and in vitro conditions. It was found that the magnitude of changes in the electrokinetic potential of nuclei induced by exposure to electromagnetic radiation of extremely high frequencies under in vivo conditions far exceeded the magnitude of the electrokinetic potential of isolated nuclei treated with electromagnetic radiation of the same frequency under in vitro conditions; this confirmed the prolonged effect of electromagnetic radiation of extremely high frequencies. The authors discuss the modulation of the electrokinetic potential depending on the change in the difference between the content of anionic phospholipids in the nuclear membrane and the soluble nuclear fraction arising under the effect of electromagnetic radiation of extremely high frequencies, which leads to a change in the surface charge of the nuclear membrane, the electrokinetic potential of the nuclei, and the formation of a more compact double electric layer.

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Authors and Affiliations

  1. Yerevan State University, 0025, Yerevan, Armenia

    L. A. Minasbekyan & A. V. Nerkararyan

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  1. L. A. Minasbekyan
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  2. A. V. Nerkararyan
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Correspondence to L. A. Minasbekyan.

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Conflict of interest. The authors declare that they have no conflicts of interest.

Statement of the welfare of humans or animals. The article does not contain any studies involving humans or animals in experiments performed by any of the authors.

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Translated by E. Puchkov

Abbreviations: EMR EHF, electromagnetic radiation of extremely high frequencies; EKP, electrokinetic potential; PL, phospholipids.

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Minasbekyan, L.A., Nerkararyan, A.V. Contribution of Nuclear Membrane Phospholipids to the Formation of Electrokinetic Potential. BIOPHYSICS 67, 921–930 (2022). https://doi.org/10.1134/S0006350922060148

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  • DOI: https://doi.org/10.1134/S0006350922060148

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