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The Antioxidant properties of para-Aminobenzoic acid and its sodium salt

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Abstract

The antioxidant properties of para-aminobenzoic acid, a substance from the group of vitamins, and its sodium salt has been found using the reaction of adrenaline autoxidation in an alkaline medium as a superoxide-generating model system. These compounds inhibited the accumulation of adrenochrome, which is a product of adrenaline oxidation, and the formation of superoxide anions, detected by their reaction with nitro blue tetrazolium. Approaches have been developed to produce a true solution of para-aminobenzoic acid and conditions were established to measure the antioxidant activity of para-aminobenzoic acid and its sodium salt. The antioxidant properties of these compounds indicate their possible participation in the redox reactions of the cell and can also be one reason that they are essential.

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Authors and Affiliations

  1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290, Russia

    T. V. Sirota & N. E. Lyamina

  2. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 119334, Russia

    L. I. Weisfeld

Authors
  1. T. V. Sirota
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  2. N. E. Lyamina
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  3. L. I. Weisfeld
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Correspondence to T. V. Sirota.

Additional information

Original Russian Text © T.V. Sirota, N.E. Lyamina, L.I. Weisfeld, 2017, published in Biofizika, 2017, Vol. 62, No. 5, pp. 846–851.

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Sirota, T.V., Lyamina, N.E. & Weisfeld, L.I. The Antioxidant properties of para-Aminobenzoic acid and its sodium salt. BIOPHYSICS 62, 691–695 (2017). https://doi.org/10.1134/S0006350917050219

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  • DOI: https://doi.org/10.1134/S0006350917050219

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