Abstract
The principle of the minimum rate of energy dissipation for conformational movements in a viscous medium formulated in an earlier study (K.V. Shaitan, Biophysics, 2015, Vol. 60, p. 692) has been applied for a theoretical estimation of the distribution functions of the energy dissipation rates for selected elements of a macromolecule. Equipartition of energy dissipation rates among the nodes of the chain upon conformational movements in the statistical limit of the process is obtained. The uniform distribution of energy dissipation rates along the chain does affect on the formation of the collective conformational degrees of freedom and the folding dynamics.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. B. Rubin, Biophysics, Vol. 1: Theoretical Biophysics (Inst. Comput. Res., Moscow—Izhevsk, 2013) [in Russian].
K. V. Shaitan and A. B. Rubin, Mol. Biol. (Moscow) 14, 1323 (1980).
K. V. Shaitan, Biofizika 39, 949 (1994).
K. V. Shaitan, in Stochastic Dynamics of Reacting Biomolecules, Ed. by W. Ebeling, L. Schimansky-Gefer, and Y. M. Romanovsky (World Scientific, Singapore, 2003), pp. 283–308.
K. V. Shaitan and S. S. Saraikin, Biophysics (Moscow) 45 (3), 397 (2000).
K. V. Shaitan, Biophysics (Moscow) 60 (5), 692 (2015).
K. V. Shaitan, M. A. Lozhnikov, and G. M. Kobelkov, Biophysics (Moscow) 61 (4), 531 (2016).
L. Onsager, Phys. Rev. 38, 2265 (1931).
I. Prigogine, Introduction to Thermodynamics of Irreversible Processes, 3rd ed. (Wiley Interscience, New York, 1968; Research Center “Regular and Stochastic Dynamics,” Izhevsk, 2001).
P. G. Wolynes, Philos. Trans. R. Soc. 363, 453 (2005).
J. N. Onuchic and P. G. Wolynes, Curr. Opin. Struct. Biol. 14, 70 (2004).
E. R. Henry, R. B. Best, and W. A. Eaton, Proc. Natl. Acad. Sci. U. S. A. 110, 17880 (2013).
A. V. Finkelstein and O. B. Ptitsyn, Protein Physics (KDU, Moscow, 2002; Academic, New York, 2002).
K. A. Dill and J. L. MacCallum, Science 338, 1042 (2012).
V. A. Zorich, Teor. Veroyatn. Primen. 59, 436 (2014).
J. W. Gibbs, Elementary Principles in Statistical Mechanics (Yale Univ. Press, New Haven, 1902; OFIZ, Moscow, 1946).
V. D. Milman, Usp. Mat. Nauk 59, 157 (2004).
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © K.V. Shaitan, 2017, published in Biofizika, 2017, Vol. 62, No. 1, pp. 5–8.
Rights and permissions
About this article
Cite this article
Shaitan, K.V. Distribution of the energy dissipation rates among degrees of freedom during conformational movements and folding of a macromolecular chain in a viscous medium. BIOPHYSICS 62, 1–4 (2017). https://doi.org/10.1134/S0006350917010183
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0006350917010183