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Effect of local hypothermia on H- and M-responses after spinal cord contusion in dogs

  • Complex Systems Biophysics
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Abstract

In this study we investigated a motor-neuronal functional state based on H- and M-responses from m. quadratus plantae in dogs before and after experimental spinal cord contusion with and without following local intraoperative hypothermia. H- and M-responses from m. quadratus plantae were recorded during stimulation of the tibial nerve and results were compared between the groups. Our results demonstrate that local hypothermia applied after spinal cord contusion reduces amplitude of both M- and H-responses and also H max/M max ratio that may indicate depression of motorneurons excitability. After spinal cord contusion with-out following hypothermia the excitability of the spinal motorneurons during post-traumatic period, in opposite, was significantly increased. These results support a conclusion that intraoperative hypothermia after spinal cord contusion can delay development of functional excitability of the motoneurons and protect from further changes in H- and M-responses.

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Authors and Affiliations

  1. Kazan Federal University, Kazan, Republic of Tatarstan, 420008, Russia

    G. G. Iafarova, A. R. Hazieva & T. V. Baltina

  2. Republican Clinical Hospital, Ministry of Health of the Republic of Tatarstan, Kazan, 420059, Russia

    G. G. Iafarova & R. F. Tumakaev

Authors
  1. G. G. Iafarova
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  2. R. F. Tumakaev
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  3. A. R. Hazieva
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  4. T. V. Baltina
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Corresponding author

Correspondence to T. V. Baltina.

Additional information

Original Russian Text © G.G. Iafarova, R.F. Tumakaev, A.R. Hazieva, T.V. Baltina, 2014, published in Biofizika, 2014, Vol. 59, No. 5, pp. 1017–1022.

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Iafarova, G.G., Tumakaev, R.F., Hazieva, A.R. et al. Effect of local hypothermia on H- and M-responses after spinal cord contusion in dogs. BIOPHYSICS 59, 829–833 (2014). https://doi.org/10.1134/S0006350914050303

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  • DOI: https://doi.org/10.1134/S0006350914050303

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