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Photomodification of blood by laser and ultraviolet radiation: a comparative study

Biophysics volume 59, pages 653–657 (2014)Cite this article

Abstract

The efficiency of in vivo blood irradiation by a laser light source (λ = 632.8 and 670 nm) and a mercury lamp (UV light, λ = 254 nm) was compared. Absorption spectra, gas content, oxyhemoglobin content, hemoglobin oxygen saturation, concentrations of lactate and glucose were studied for both irradiated and control samples. Hemoglobin was assumed to be the primary photoacceptor of light radiation for the indicated wavelengths. No substantial differences have been found between the effects of laser and non-laser irradiation. We conclude that the biological impact of the procedure is related to photoinduced changes in hemoglobin oxygen saturation.

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References

  1. V. I. Karandashov, E. B. Petukhov, and V. S. Zrodnikov, Phototherapy, Ed. by N. R. Paleev (Meditsina, Moscow, 2001) [in Russian].

  2. G. I. Klebanov, N. Yu. Shuraeva, T. V. Chichuk, et al., Biophysics 51, 94 (2006).

    Article  Google Scholar 

  3. G. I. Klebanov, N. Yu. Shuraeva, T. V. Chichuk, et al., Biophysics 51, 285 (2006).

    Article  Google Scholar 

  4. T. I. Karu, in Low-power Laser Therapy (2003), pp. 4825–4841.

    Google Scholar 

  5. G. K. Reddy, Lasers Surg. Med. 33, 344 (2003).

    Article  Google Scholar 

  6. O. Schuhfiled, M. Korpan, and V. Fialka-Moser, Lasers Med. Sci. 15, 169 (2000).

    Article  Google Scholar 

  7. N. A. Zhevago, K. A. Samoilova, and K. D. Obolenskaya, Photochem. Photobiol. Sci. 3, 102 (2004).

    Article  Google Scholar 

  8. V. V. Tuchin, L. V. Wang, and D. A. Zimnyakov, in Optical Polarization in Biomedical Application (Springer, 2006), pp. 111–138.

    Google Scholar 

  9. B. Klitzman, http://www.bioptron.co.za/PDF/Studies/DUKEUNIVERSITY.USA-SkinpenetrationofPolarizedI.PDF.

  10. Y. M. Mostafa, S. N. Amin, S. Abdalwahab, and A. AM. Elsherbin, Blood Disorders Transf. 4(1), 2 (2013).

    Google Scholar 

  11. G. A. Zalesskaya and V. S. Ulashchik, Zh. Prikl. Spektrosk. 76(1), 51 (2009).

    Google Scholar 

  12. J. Mobley and T. Vo-Dinh, Biomedical Photonics Handbook (Boca Raton, London, New York, Washington, 2003), Ch. 2/1.

    Google Scholar 

  13. M. Yu. Tars’ev and V. V. Ryl’kov, Biokhimiya 56, 1296 (1991).

    Google Scholar 

  14. G. A. Zalesskaya and T. O. Maslova, Optika Spektrosk. 110(2), 337 (2011).

    Google Scholar 

  15. G. A. Zalesskaya, Photomodification of Blood by Therapeutic Doses of Optical Radiation, Ed. by V. S. Ulashchik (Belorusskaya Nauka, Minsk, 2014) [in Russian].

  16. N. K. Zenkov, V. Z. Lankin, and Men’shikova,Oxidative Stress: Biochemical and PathoPhysiological Aspects (Nauka/Interperiodica, Moscow, 2001) [in Russian].

    Google Scholar 

  17. G. A. Zalesskaya and O. V. Laskina, Zh. Prikl. Spektrosk. 80(1), 115 (2013).

    Google Scholar 

  18. G. A. Zalesskaya, O. V. Laskina, N. P. Mit’kovskaya, and I. I. Kirkovskii, Biomed. Radioelektron., no. 12, 3 (2011).

    Google Scholar 

  19. G. A. Zalesskaya, O. V. Laskina, N. P. Mit’kovskaya, and I. I. Kirkovskii, Zh. Prikl. Spektrosk. 79(3), 465 (2012).

    Google Scholar 

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Authors and Affiliations

  1. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk, 220072, Belarus

    G. A. Zalesskaya & I. I. Kalosha

Authors
  1. G. A. Zalesskaya
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  2. I. I. Kalosha
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Correspondence to G. A. Zalesskaya.

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Original Russian Text © G.A. Zalesskaya, I.I. Kalosha, 2014, published in Biofizika, 2014, Vol. 59, No. 4, pp. 799–804.

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Zalesskaya, G.A., Kalosha, I.I. Photomodification of blood by laser and ultraviolet radiation: a comparative study. BIOPHYSICS 59, 653–657 (2014). https://doi.org/10.1134/S0006350914040265

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  • DOI: https://doi.org/10.1134/S0006350914040265

Keywords

  • UV blood irradiation
  • hemoglobin
  • reactive oxygen species