Skip to main content
SpringerLink
Log in

Conformationally stable segments in helical structures of polypeptide chains of proteins and their role in high level structures formation

  • Complex Systems Biophysics
  • Published:
Biophysics Aims and scope Submit manuscript

Abstract

In the work the arguments are presented in favor of the idea on the role of conformationally stable oligopeptides in specific long-distance interactions in phenomena of molecular recognition during various biological processes. Original authors’ and literature data are taken into account. The examples of conformationally stable short oligopeptides participating in alpha-helix and collagen type structures formation are given simultaneously with theoretical approaches. The conformationally stable oligopeptides obtained in the course of PDB bank analysis are discussed. The role of amino acid sequence in collagen helix formation is shown.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. C. Levinthal, J. Chem. Phys. 65, 44 (1968).

    Google Scholar 

  2. A. V. Finkelstein and A. Ya. Badretdinov, Fold. Des. 2, 11 (1007).

    Google Scholar 

  3. P. L. Privalov, Adv. Prot. Chem. 33, 167 (1979).

    Article  Google Scholar 

  4. P. L. Privalov and N. N. Khechinashvili, J. Mol. Biol. 86, 665 (1974).

    Article  Google Scholar 

  5. P. L. Privalov and Yu. V. Griko, J. Mol. Biol. 190, 487 (1986).

    Article  Google Scholar 

  6. M. R. Pincus and H. A. Scheraga, J. Phys. Chem. 81, 1579 (1977).

    Article  Google Scholar 

  7. D. Baker, Nature 405(6782), 39 (2000).

    Article  ADS  Google Scholar 

  8. V. U. Johanson, V. Zoete, and N. Guex, Int. J. Mol. Sci. 14, 7795 (2013).

    Article  Google Scholar 

  9. V. A. Namiot, A. V. Batyanovskii, I. V. Filatov, et al., Physics Lett. A 375, 2911 (2011).

    Article  ADS  Google Scholar 

  10. A. V. Batyanovskii, I. V. Filatov, V. A. Namiot et al., Biophysics 57, 831 (2012).

    Article  Google Scholar 

  11. A. V. Batyanovskii and P. K. Vlasov, Biophysics 53, 264 (2008).

    Article  Google Scholar 

  12. A. A. Anashkina, E. N. Kuznetsov, N. G. Esipova, and V. G. Tumanyan, Proteins 67, 1060 (2007).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Cell Biophysics and Cell Technology, National Academy of Sciences of Belarus, Minsk, 220072, Belarus

    A. V. Batyanovskii & I. D. Volotovsky

  2. Institute of Nuclear Physics, Moscow State University, Moscow, 119992, Russia

    V. A. Namiot

  3. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia

    I. V. Filatov, M. V. Moldaver, A. A. Anashkina, V. G. Tumanyan & N. G. Esipova

Authors
  1. A. V. Batyanovskii
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. A. Namiot
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I. V. Filatov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. V. Moldaver
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. A. Anashkina
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. V. G. Tumanyan
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. N. G. Esipova
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. I. D. Volotovsky
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. V. Batyanovskii.

Additional information

Original Russian Text © A.V. Batyanovskii, V.A. Namiot, I.V. Filatov, M.V. Moldaver, A.A. Anashkina, V.G. Tumanyan, N.G. Esipova, I.D. Volotovsky, 2013, published in Biofizika, 2013, Vol. 58, No. 6, pp. 1069–1073.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Batyanovskii, A.V., Namiot, V.A., Filatov, I.V. et al. Conformationally stable segments in helical structures of polypeptide chains of proteins and their role in high level structures formation. BIOPHYSICS 58, 841–844 (2013). https://doi.org/10.1134/S0006350913060043

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0006350913060043

Keywords

Search

Navigation