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Copper-induced change in the ESR signal of hemoglobin nitrosyl complexes in wound by the action of copper nanoparticles

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Abstract

The results concerning changes in the ESR signal of hemoglobin nitrosyl complexes in wound tissues in the course of healing by the action of ointments with copper nanoparticles (patent N2460532, Russia) are presented. It is shown that the wound healing process modified by the influence of copper nanoparticles demonstrates the increase in the ESR signal amplitude for hemoglobin nitrosyl complexes as compared with controls (the ointment base without nanoparticles). Planimetric measurements of wound area through reparation course indicate an active process of wound healing for injuries treated with copper nanoparticles in the ointment, resulting in lessening half-reparation time up to 5.0 times as compared with controls (treatment with the ointment base). The paper discusses the role of copper nanoparticles, NO and their potential synergistic effect on the skin wound regeneration.

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References

  1. Radicals for Life: The Various Forms of Nitric Oxide, Ed. by E. Van Feasen and A. Vanin (Publisher: Elsevier Science, Amsterdam, 2007).

    Google Scholar 

  2. A. N. Osipov, G. G. Borisenko, and Yu. A. Vladimirov, Uspekhi Biol. Khimii 47, 259 (2007).

    Google Scholar 

  3. J. S. Isenberg, L. A. Ridnour, M. G. Espey, and D. A. Wink, Microsurgery 25(5), 442 (2005).

    Article  Google Scholar 

  4. A. B. Shekhter, T. G. Rudenko, V. A. Serezhenkov, and A. F. Vanin, Biophysics (Moscow) 52, 515 (2007).

    Article  Google Scholar 

  5. M. Scheïa and P. Mulater, Am. J. Clin. Invest. 12, 388 (2007).

    Google Scholar 

  6. A. A. Rakhmetova, T. P. Alekseeva, O. A. Bogoslovskaya, et al., Ros. Nanotekhnologii 5(3–4), 102 (2010).

    Google Scholar 

  7. A. A. Rakhmetova, O. A. Bogoslovskaya, A. N. Ganzhigaeva, et al., Vestn. RUDN Ser. Med, no. 4, 139 (2011).

    Google Scholar 

  8. A. N. Ganzhigaeva, M. D. Mbasha, N. L. Mbilini, et al., in Proc. IV Internat. Sci. Conf. “SCIENCE4HEALTH” (Moscow, 2012), pp. 127–128.

    Google Scholar 

  9. O. A. Bogoslovskaya, A. A. Rakhmetova, N. N. Glushchenko et al., Patent 2460532. Byul. Izobret. No. 25 (2012).

    Google Scholar 

  10. M. Ya. Gen and A. V. Miller, Auth. Certif. USSR no. 814432. Byul. Izobret. No. 11, 25 (1981).

    Google Scholar 

  11. A. N. Minchenko, Wounds. Treatment and Prophylaxis of Complications (Izd. SpetsLit, 2003) [in Russian].

    Google Scholar 

  12. Yu. K. Abaev, Med. Novosti, no. 6, 3 (2003).

    Google Scholar 

  13. N. N. Glushchenko, I. P. Ol’khovskaya, T. V. Pleteneva, et al., Izv. AN SSSR Ser. Biol., no. 3, 415 (1989).

    Google Scholar 

  14. G. A. Lushcheikin, Polymeric Piezoelectrics (Khimiya, Moscow, 1990) [in Russian].

    Google Scholar 

  15. L. I. Shu-Tong and Fn. Elton Katz, Bipolys. 15, 1439 (1976).

    Article  Google Scholar 

  16. H. Ohshima and S. Ohki, Biophys. J. 47(5), 613 (1985).

    Article  Google Scholar 

  17. Yu. I. Fedorov, L. A. Volodina, T. A. Kuzovnikova, and V. S. Lebedev, Izv. AN SSSR Ser. Biol., no. 1, 153 (1984).

    Google Scholar 

  18. L. Pickart, J. Biomater Sci. Polym. Ed. 19(8), 969 (2008).

    Article  Google Scholar 

  19. M. K. Pulatova, G. T. Rikhtereva, and Z. V. Kuropteva, Electron Paramagnetic Resonance of Molecular Radiobiology (Energoatomizdat, Moscow, 1989) [in Russian].

    Google Scholar 

  20. H. L. Elfod, GANN Monograph on Cancer Research 13, 205 (1972).

    Google Scholar 

  21. L. A. Volodina, A. N. Zhigach, I. O. Leipunskii, et al., Biofizika 54(6), 1060 (2009) [no English version].

    Google Scholar 

  22. E. N. Kukhtina and N. N. Gluschenko, Biokhimiya 6, 993 (1996).

    Google Scholar 

  23. O. A. Bogoslovskaya, I. P. Ol’khovskaya, and N. N. Gluschenko, Izv. RAN Ser. Biol., no. 2, 180 (2000).

    Google Scholar 

  24. A. B. Shekher, V. A. Serezhenkov, T. G. Rudenko, et al., Nitric Oxide. Biol. Chem. 12(4), 210 (2005).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Tal’roze Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Moscow, 119334, Russia

    L. A. Volodina, A. A. Rakhmetova, O. A. Bogoslovskaja, I. P. Olkhovskaya & N. N. Gluschenko

  2. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 119334, Russia

    L. M. Bayder

Authors
  1. L. A. Volodina
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  2. L. M. Bayder
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  3. A. A. Rakhmetova
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  4. O. A. Bogoslovskaja
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  5. I. P. Olkhovskaya
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  6. N. N. Gluschenko
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Corresponding author

Correspondence to N. N. Gluschenko.

Additional information

Original Russian Text © L.A. Volodina, L.M. Bayder, A.A. Rakhmetova, O.A. Bogoslovskaja, I.P. Olkhovskaya, N.N. Gluschenko, 2013, published in Biofizika, 2013, Vol. 58, No. 5, pp. 876–881.

Editor’s Note: This is the closest possible equivalent of the original publication with all its practical details, statements and terminology, phrasing and style, so the reader can make sound judgment; English title, Abstract and keywords provided by authors. A.G.

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Volodina, L.A., Bayder, L.M., Rakhmetova, A.A. et al. Copper-induced change in the ESR signal of hemoglobin nitrosyl complexes in wound by the action of copper nanoparticles. BIOPHYSICS 58, 693–698 (2013). https://doi.org/10.1134/S0006350913050175

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