Abstract
We have studied the dynamics of reentry inside the sinoatrial node (SAN). We have found that reentry is unstable at high intercellular conductance. Rotating reentry induces a slow migrating crescent-shaped functional block near the SAN boundary. Abnormal conduction from atrial tissue into the SAN occurs after decay of the reentry. Acetylcholine increases the lifespan of reentry in the SAN.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
R. R. Aliev and A. B. Rovinsky, J. Phys. Chem. 96, 732 (1992).
R. R. Aliev, Chaos Solitons Fractals 5, 567 (1995).
O. F. Hutter and W. Trautwein, J. Gen. Physiol. 39, 715 (1956).
L. V. Rozenshtraukh, A. V. Kholopov, and A. V. Yushmanova, Biofizika 15, 690 (1970).
L. V. Rozenshtraukh, R. R. Aliev, G. G. Beloshapko, and A. V. Yushmanova, Kardiologiya 4, 4 (2007).
R. A. Syunyaev and R. R. Aliev, RJNAMM 26, 575 (2011).
H. Zhang, A. V. Holden, I. Kodama, et al., Am. J. Physiol. 279, H397 (2000).
H. Zhang, A. V. Holden, and M. R. Boyett, Circ. 103, 584 (2001).
R. R. Aliev, V. V. Fedorov, and L. V. Rozenshtraukh, Dokl. RAN 397, 697 (2004).
R. R. Aliev, V. V. Fedorov, and L. V. Rozenshtraukh, Dokl. RAN 402, 548 (2005).
R. R. Aliev and L. M. Chailakhyan, Dokl. RAN 402, 689 (2005).
R. A. Syunyaev and R. R. Aliev, Biofizika 54, 77 (2009).
R. R. Aliev and A. Yu. Furs, Biofizika 55, 496 (2010).
R. R. Aliev, Conceptual and Detailed Models of the Electrical Activity of Myocardium (Lambert Acad. Publ., 2012), ISBN 978-3-8465-3943-9.
D. S. Lindblad, C. R. Murphey, J. W. Clark, and W. R. Giles, Am. J. Physiol. 271, H1666 (1996).
R. A. Syunyaev and R. R. Aliev, Biofizika 55, 1132 (2010).
R. R. Aliev and V. N. Biktashev, J. Phys. Chem. 98, 9676 (1994).
R. A. Syunyaev and R. R. Aliev, RJNAMM, 27(5) (2012, in press).
V. V. Fedorov, A. V. Glukhov, and R. Chang, Am. J. Physiol. 302, H1773 (2012).
A. V. Glukhov, L. T. Hage, C. A. Carnes, et al., Circulation (in press).
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © R.A. Syunyaev, R.R. Aliev, 2012, published in Biofizika, 2012, Vol. 57, No. 5, pp. 870–875.
Rights and permissions
About this article
Cite this article
Syunyaev, R.A., Aliev, R.R. Computer simulation of microreentry in the sinoatrial node. BIOPHYSICS 57, 676–680 (2012). https://doi.org/10.1134/S0006350912050211
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0006350912050211