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Using operonic gene pairs to set the threshold correlation coefficient for differently expressed genes

  • Molecular Biophysics
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Abstract

We have developed an approach to estimating the correlations in the noise component of gene expression data. An efficient noise reduction technique has been suggested. The resulting methods have been applied to E. coli microarray data and tested on SOS response modulated genes.

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Authors and Affiliations

  1. Centre for DNA Fingerprinting and Diagnostics, Hyderabad, 500 001, India

    Sh. Hedge & Sh. Mande

  2. Faculty of Bioengineering and Bioinformatics, Moscow State University, Moscow, 119991, Russia

    E. Yu. Klimova

  3. Scientific Center GosNIIgenetika, Moscow, 117545, Russia

    Yu. A. Medvedeva, V. Yu. Makeev & E. A. Permina

  4. Vavilov Insitute for General Genetics, Moscow, 119991, Russia

    Yu. A. Medvedeva, V. Yu. Makeev & E. A. Permina

  5. Engelhardt Institute of Molecular Biology, Moscow, 119991, Russia

    V. Yu. Makeev

Authors
  1. Sh. Hedge
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  2. E. Yu. Klimova
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  3. Sh. Mande
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  4. Yu. A. Medvedeva
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  5. V. Yu. Makeev
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  6. E. A. Permina
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Corresponding author

Correspondence to E. A. Permina.

Additional information

Original Russian Text © Sh. Hedge, E.Yu.Klimova, Sh. Mande, Yu.A. Medvedeva, V.Yu. Makeev, E.A. Permina, 2011, published in Biofizika, 2011, Vol. 56, No. 6, pp. 1062–1064.

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Hedge, S., Klimova, E.Y., Mande, S. et al. Using operonic gene pairs to set the threshold correlation coefficient for differently expressed genes. BIOPHYSICS 56, 1041–1042 (2011). https://doi.org/10.1134/S0006350911060078

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  • DOI: https://doi.org/10.1134/S0006350911060078

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