Skip to main content
SpringerLink
Log in

Prospects of using magnetic nanoparticles to potentiate the anticarcinogenic action of dinitrosyl iron complexes with thiol ligands

  • Nanotechnologies in Medicine and Industry
  • Published:
Biophysics Aims and scope Submit manuscript

Abstract

Low-molecular dinitrosyl iron complexes with thiol-containing ligands (cysteine or glutathione) have recently been shown to be capable of modulating apoptosis. Being in the intact state, the complexes prevent apoptosis, and when decomposed, they initiate it. The possibility is considered of delivering the complexes to tumor tissues by ferromagnetic nanoparticles driven by an external magnetic field.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. F. Vanin, Nitric Oxide: Biol. Chem. 21, 1 (2009).

    Article  Google Scholar 

  2. Y. P. Vedernikov, P. I. Mordvintcev, I. V. Malenkova, et al., Eur. J. Pharmacol. 211, 313 (1992).

    Article  Google Scholar 

  3. F. W. Flitney, I. L. Megson, D. E. Flitney, et al., Br. J. Pharmacol. 107, 842 (1992).

    Google Scholar 

  4. A. F. Vanin, V. P. Mokh, V. A. Serezhenkov, et al., Nitric Oxide: Biol. Chem. 16, 322 (2007).

    Article  Google Scholar 

  5. A. L. Kleschyov, P. I. Mordvintcev, and A. F. Vanin, Studia Biofizika 105, 93 (1985).

    Google Scholar 

  6. P. I. Mordvintcev, M. D. Putintsev, M. E. Galagan, et al., Byul. Vsesoyuz. Kardiol. Nauch. Tsentra, no. 1, 46 (1988).

  7. M. E. Galagan, Е. В. Орановская, P. I. Mordvintcev и др., Byul. Vsesoyuz. Kardiol. Nauch. Tsentra, no. 2, 75 (1988).

  8. V. L. Lakomkin, A. F. Vanin, A. A. Timoshin, et al., Nitric Oxide: Biol. Chem. 16, 413 (2007).

    Article  Google Scholar 

  9. A. B. Shekhter, T. G. Rudenko, V. A. Serezhenkov, et al., Biophysics 52, 515 (2007).

    Article  Google Scholar 

  10. E. I. Veliev, S. V. Kotov, V. K. Shishlo, et al., Biophysics 53, 153 (2008).

    Article  Google Scholar 

  11. A. A. Andreev-Andrievsky, V. D. Mikoyan, and A. F. Vanin, Nitric Oxide: Biol. Chem. (in press).

  12. L. J. Ignarro, Nitric Oxide: Biology and Pharmacology (Academic Press, San Diego, 2000).

    Google Scholar 

  13. A. J. Vithaythil, J. L. Ternberg, and B. Commoner, Nature 207, 1246 (1965).

    Article  ADS  Google Scholar 

  14. A. F. Vanin, L. A. Blumenfeld, and A. G. Chetverikov, Biofizika 12, 829 (1967).

    Google Scholar 

  15. J. R. Lancaster and J. B. Hibbs, Proc. Natl. Acad. Sci. USA 87, 1223 (1990).

    Article  ADS  Google Scholar 

  16. C. Pellat, Y. Henry, and J.-C. Drapier, Biochim. Biophys. Res. Comm. 166, 119 (1990).

    Article  Google Scholar 

  17. A. F. Vanin, P. I. Mordvintcev, S. Hauschildt, et al., Biochim. Biophys. Acta 1177, 37 (1993).

    Article  Google Scholar 

  18. J. Stadler, H. A. Bergonia, M. DiSilvio, et al., Arch. Biochem. Biophys. 302, 4 (1993).

    Article  Google Scholar 

  19. A. K. Nussler, D. A. Geller, M. A. Sweetland, et al., Biochem. Biophys. Res. Comm. 194, 826 (1993).

    Article  Google Scholar 

  20. Y.-L. Geng, A.-S. Petersson, A. Wennmalm, et al., Exp. Cell Res. 214, 418 (1994).

    Article  Google Scholar 

  21. K. Doi, T. Akaike, H. Horie, et al., Cancer 77, 1598 (1996).

    Google Scholar 

  22. V. D. Mikoyan, M. A. Serezhenkov, N. V. Brazhnikova, et al., Biofizika 41, 110 (2004).

    Google Scholar 

  23. R. N. Watts, C. Hawkins, P. Ponka, et al., Proc. Natl. Acad. Sci. USA 103, 7670 (2006).

    Article  ADS  Google Scholar 

  24. Y. M. Kim, H. T. Chang, R. L. Simmons, et al., J. Biol. Chem. 275, 10954 (2000).

    Article  Google Scholar 

  25. F. Feger, H. Ferry-Dumazet, M. M. Matsuda, et al., Cancer Res. 61, 5289 (2001).

    Google Scholar 

  26. H. Ferry-Dumazet, M. M. Matsuda M. Dupouy, et al., Leukemia 16, 708 (2002).

    Article  Google Scholar 

  27. V. A. Serezhenkov, E. V. Kalinina, V. A. Glazunova, et al., Biofizika 52, 869 (2007) [no English version].

    Google Scholar 

  28. N. Y. Giliano, L. V. Konevega, L. A. Noskin, et al., Nitric Oxide: Biol. Chem. (in press).

  29. A. L. Kleschyov, S. Strand, S. Schmitt, et al., Free Rad. Biol. Med. 40, 1340 (2006).

    Article  Google Scholar 

  30. O. S. Zhukova, N. A. Sanina, L. V. Fetisova, et al., Ros. Bioterap. Zh. 5, 14 (2006).

    Google Scholar 

  31. S. V. Vasil’eva, E. Yu. Moshkovskaya, A. S. Terekhov, et al., Ros. Genet. Zh. 42, 737 (2006).

    Article  Google Scholar 

  32. S. V. Vasil’eva, A. N. Osipov, N. A. Sanina, et al., Dokl. RAN 414, 102 (2007).

    Google Scholar 

  33. M. Kruszewski, H. Lewandowska, R. P. Starzynski, et al., Free Rad. Biol. Med. 36, S51 (2004).

    Article  Google Scholar 

  34. A. F. Vanin, I. V. Malenkova, P. I. Mordvintcev, and A. Myulsh, Biokhimiya 58, 1094 (1993).

    Google Scholar 

  35. A. F. Vanin, I. V. Malenkova, and V. A. Serezhenkov, Nitric Oxide: Biol. Chem. 1, 191 (1997).

    Article  Google Scholar 

  36. A. F. Vanin, A. A. Papina, V. A. Serezhenkov, et al., Nitric Oxide: Biol. Chem. 10, 60 (2004).

    Article  Google Scholar 

  37. A. F. Vanin, N. A. Sanina, V. A. Serezhenkov, et al., Nitric Oxide, Biol. Chem. 16, 82 (2007).

    Article  Google Scholar 

  38. I. M. Rio-Echevarria, R. Tavano, V. Causin, et al., J. Am. Chem. Soc. 133, 8 (2011).

    Article  Google Scholar 

  39. S. J. H. Soenen, U. Himmelreich, N. Nuytten, et al., Small 6, 2136 (2010).

    Article  Google Scholar 

  40. K. Buyukhatipoglu and A. M. Clyne, J. Biomed. Material Res. 96, 186 (2010).

    Google Scholar 

  41. Y. Wang, M. T. Zhu, B. Wang, et al., J. Nanosci. Nanotechnol. 10, 8550 (2010).

    Article  Google Scholar 

  42. M. A. Voinov, J. O. Sosa Pagan, E. Morrison, et al., J. Am. Chem. Soc. 133, 35 (2011).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, 119991, Russia

    A. F. Vanin

Authors
  1. A. F. Vanin
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Original Russian Text © A.F. Vanin, 2011, published in Biofizika, 2011, Vol. 56, No. 5, pp. 868–872.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vanin, A.F. Prospects of using magnetic nanoparticles to potentiate the anticarcinogenic action of dinitrosyl iron complexes with thiol ligands. BIOPHYSICS 56, 832–835 (2011). https://doi.org/10.1134/S0006350911050228

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0006350911050228

Keywords

Search

Navigation