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Computer modeling of nonlinear heart rate dynamics during train extracardial impulsation in the sinoatrial node

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Abstract

A computer model of excitation conduction in the heart has been employed to study the nonlinear heart rate dynamics under stress loads. The modeling was aimed to test the hypothesis explaining changes in the heart rate dynamics during nociceptive stress loads by the occurrence of train extracardial impulsation arriving at the sinoatrial node. The computer simulation shows that, with a particular set of parameters, the model imitates the dynamics of RR intervals observed in experiments. The present model provides a unified theoretical basis for further simulation of various types of ventricular disturbances under external extreme loads.

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References

  1. L. V. Mezentseva, Vestn. Novykh Med. Tekhnol. 16(1), 196 (2009).

    Google Scholar 

  2. L. V. Mezentseva, Ros. Fisiol. Zh. I.M. Sechenova (in press).

  3. Yu. B. Abramov, A. Yu. Kozlov, and L. V. Mezentseva, Vestn. Novykh Med. Tekhnol. 12(3), 55 (2005).

    Google Scholar 

  4. Yu. B. Abramov, A. Yu. Kozlov, O. N. Konovalov, et al., Vestn. Novykh Med. Tekhnol. 15(2), 9 (2008).

    Google Scholar 

  5. Human Physiology, Ed. by R. Shmidt and G. Tevs (Mir, Moscow, 1996), Vol. 2 [in Russian].

    Google Scholar 

  6. E. I. Chazov, Diseases of Heart and Vessels (Meditsina, Moscow, 1993) [in Russian].

    Google Scholar 

  7. D. A. Barton, T. Dawood, E. A. Lambert, et al., J. Hypertension 25, 2117 (2007).

    Article  Google Scholar 

  8. M. Esler, E. Lambert, and M. Alvarenga, Stress and Health, 24, 196 (2008).

    Article  Google Scholar 

  9. B. I. Balanter, M. A. Khanin, and D. S. Chenavsky, Introduction to Mathematical Modeling of Pathological Processes (Meditsina, Moscow, 1980) [in Russian].

    Google Scholar 

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Original Russian Text © L.V. Mezentseva, 2011, published in Biofizika, 2011, Vol. 56, No. 2, pp. 322–327.

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Mezentseva, L.V. Computer modeling of nonlinear heart rate dynamics during train extracardial impulsation in the sinoatrial node. BIOPHYSICS 56, 281–285 (2011). https://doi.org/10.1134/S0006350911020229

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  • DOI: https://doi.org/10.1134/S0006350911020229

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