Autoimmune processes after long-term low-level exposure to electromagnetic fields part 4. Oxidative intracellular stress response to the long-term rat exposure to nonthermal RF EMF

Abstract

Forty eight male Wistar rats with initial weight of 200–220 g were exposed to EMF of 2450 MHz frequency and 500 μW/cm2 intensity for 7 h daily over a period of 30 days. On the seventh and 14th days after completion of exposure to the long-term EMF, enzyme immunoassay revealed a significant increase in the amount of specific antibodies of the IgM and IgG classes against the compounds yielded by interaction of amino acids with nitric oxide and its derivatives; tryptophan metabolites; azelaic acid; small-chain fatty acids; small-chain hydroxylated fatty acids; and palmitic, myristic, and oleic acids.

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Correspondence to Y. G. Grigoriev.

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Original Russian Text © Y.G. Grigoriev, V.F. Mikhailov, A.A. Ivanov, V.N. Maltsev, A.M. Ulanova, N.M. Stavrakova, I.A. Nikolaeva, O. A. Grigoriev, 2010, published in Radiatsionnaya Biologiya. Radioekologiya, 2010, Vol. 50, No. 1, pp. 22–27.

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Grigoriev, Y.G., Mikhailov, V.F., Ivanov, A.A. et al. Autoimmune processes after long-term low-level exposure to electromagnetic fields part 4. Oxidative intracellular stress response to the long-term rat exposure to nonthermal RF EMF. BIOPHYSICS 55, 1054–1058 (2010). https://doi.org/10.1134/S0006350910060308

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Keywords

  • electromagnetic fields of microwave frequency
  • immunoglobulins
  • antibodies
  • stress
  • reactive oxygen species
  • nitric oxide
  • amino acids
  • small-chain fatty acids
  • kynurenine pathway