Abstract
A comparative investigation of the dynamics of contractile properties of the whole soleus muscle and its fibers during 3- and 12-day-long hindlimb suspension of Wistar rats and Mongolian gerbils (Meriones unguiculatus) has been performed. The data obtained indicate that the structural and functional changes caused by hypogravity in gerbils are slowed down compared with rats. A very intense drop in water content in gerbils was found, which can cause shifts in the ionic strength of the intracellular space of the muscle fiber. As a result, the proteolytic activity of enzymes may change, which can induce a less pronounced reduction in Z-disk and M-line stiffness and contractile capabilities in gerbils compared with rats.
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Original Russian Text © I.V. Ogneva, V.A. Kurushin, M.M. Glashev, E.V. Mikhailova, E.V. Ponomareva, E.G. Altaeva, I.I. Krivoi, B.S. Shenkman, 2010, published in Biofizika, 2010, Vol. 55, No. 6, pp. 1117–1123.
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Ogneva, I.V., Kurushin, V.A., Glashev, M.M. et al. Comparative analysis of structural and functional characteristics of soleus muscle in rats and mongolian gerbils during gravitational unloading of different duration. BIOPHYSICS 55, 1013–1018 (2010). https://doi.org/10.1134/S0006350910060217
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DOI: https://doi.org/10.1134/S0006350910060217