Abstract
It has been found that inhibition of the activity of protein kinase LOSK reduces the ability of cells to perform directed movement over the substrate and changes the parameters of interaction of cells with the substrate. It is suggested that chaotization of microtubules leads to stabilization of cell contacts with the substrate and, consequently, to slowdown of locomotion.
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Original Russian Text © A.V. Burakov, E.S. Nadezhdina, 2010, published in Biofizika, 2010, Vol. 55, No. 6, pp. 996–1001.
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Burakov, A.V., Nadezhdina, E.S. Protein kinase LOSK regulates the network of microtubules and cell locomotion. BIOPHYSICS 55, 916–920 (2010). https://doi.org/10.1134/S0006350910060059
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DOI: https://doi.org/10.1134/S0006350910060059