Abstract
The duration of the preautomatic pause as a function of sinoatrial node, the type of pacemaker cells, acetylcholine concentration, the duration of high-frequency stimulation, and the conductivity of gap junctions has been studied. It was found that the preautomatic pause in peripheral pacemakers occurs at a higher concentration of acetylcholine as compared with central pacemakers. The dependence of the duration of the preautomatic pause on the gap junction conductivity is a nonlinear one.
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Abbreviations
- PAP:
-
preautomatic pause
- SAN:
-
sinoatrial node
References
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Original Russian Text © R.R. Aliev, A.Yu. Furs, 2010, published in Biofizika, 2010, Vol. 55, No. 3, pp. 496–499.
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Aliev, R.R., Furs, A.Y. Computer simulation of the preautomatic pause in pacemaker cells of the sinoatrial node. BIOPHYSICS 55, 438–441 (2010). https://doi.org/10.1134/S0006350910030140
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DOI: https://doi.org/10.1134/S0006350910030140