Skip to main content
Log in

The fibrillar part of the complement factor C1q has a great amount of bound water

  • Molecular Biophysics
  • Published:
Biophysics Aims and scope Submit manuscript

Abstract

The mass of sC1q-CLR (fragment of the fibrillar part of complement factor C1q) was determined using high- and low-speed analytical ultracentrifugation. The value obtained is essentially higher than the one expected from the amino acid and carbohydrate composition. In addition, these fragments have an unusually high partial specific volume. These data support the earlier model according to which the N-terminal segment of the fibrillar structure contains an abnormally large amount of bound water.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. V. M. Tischenko, A. M. Ichtchenko, C. V. Andreyev, and A. V. Kajava, J. Mol. Biol. 234, 654 (1993).

    Article  Google Scholar 

  2. B. Brodsky-Doyle, K. R. Leonard, and K. B. M. Reid, Biochem. J. 159, 279 (1976).

    Google Scholar 

  3. E. Kilchherr, H. Hofmann, W. Steigemann, and J. Engel, J. Mol. Biol. 186, 403 (1985).

    Article  Google Scholar 

  4. S. Ruiz, A. H. Henschen-Edman, and A. J. Tenner, J. Biol. Chem. 270, 30627 (1995).

    Article  Google Scholar 

  5. D. A. Yphantis, Biochemistry 3, 297 (1964).

    Article  Google Scholar 

  6. K. E. Van Holde and R. L. Baldwin, J. Phys. Chem. 62, 734 (1958).

    Article  Google Scholar 

  7. P. L. Privalov, E. I. Tiktopulo, and V. M. Tischenko, J. Mol. Biol. 127, 203 (1979).

    Article  Google Scholar 

  8. S. J. Edelstein and H. K. Schachman, J. Biol. Chem. 242, 306 (1967).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Original Russian Text © V.M. Tischenko, 2009, published in Biofizika, 2009, Vol. 54, No. 6, pp. 1012–1014.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tischenko, V.M. The fibrillar part of the complement factor C1q has a great amount of bound water. BIOPHYSICS 54, 681–682 (2009). https://doi.org/10.1134/S0006350909060037

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0006350909060037

Key words

Navigation