Abstract
The equilibrium configurations of a circular closed DNA molecule, from the ring to the first supercoil (figure of eight), have been determined by the methods of elasticity theory. The description of the topological characteristics allows one to assess the linking number, twisting, writhing, and supercoil density immediately from the model for any equilibrium configuration of the DNA molecule. This enables one to estimate the influence of external factors on the properties and the state of closed DNA molecules.
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Original Russian Text © A.V. Shirko, A.N. Kamlyuk, V.B. Nemtsov, 2009, published in Biofizika, 2009, Vol. 54, No. 3, pp. 418–424.
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Shirko, A.V., Kamlyuk, A.N. & Nemtsov, V.B. Circular closed DNA. Theory of formation of the first supercoil. BIOPHYSICS 54, 291–295 (2009). https://doi.org/10.1134/S000635090903004X
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DOI: https://doi.org/10.1134/S000635090903004X