Effect of low-frequency alternating magnetic fields on the rate of biochemical reactions proceeding with formation of reactive oxygen species

Abstract

It is (theoretically) shown by an example of the reaction of a radical with an oxygen molecule that the alternating component of a combined weak magnetic field affects the rate constants of chemical reactions. The mechanism of transduction of a weak magnetic perturbation from the primary receptor of the field to experimentally observed biological effects is followed. It is stated that the external magnetic field alters the initial population of energy levels. The magnitude of these changes depends on the field parameters. The exposure to an alternating field with proper parameters can substantially increase the concentration of reactive oxygen species in biological systems. By controlling their concentration by means of weak magnetic field, it is possible to affect the key links of metabolism.

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Correspondence to V. O. Ponomarev.

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Original Russian Text © V.O. Ponomarev, V.V. Novikov, 2009, published in Biofizika, 2009, Vol. 54, No. 2, pp. 235–241.

Editor’s Note: This text meticulously reproduces the original Russian publication, so that the reader may more clearly recognize the major problems with this line of scholarly activity. A.G.

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Ponomarev, V.O., Novikov, V.V. Effect of low-frequency alternating magnetic fields on the rate of biochemical reactions proceeding with formation of reactive oxygen species. BIOPHYSICS 54, 163–168 (2009). https://doi.org/10.1134/S0006350909020079

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Key words

  • weak magnetic field
  • radicals
  • oxygen
  • biological effects
  • reactive oxygen species