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Disturbance of the radial system of interphase microtubules in the presence of excess serum in cell culture medium

  • Cell Biophysics
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Abstract

The work is focused on the intracellular role of microtubule organization. The population of Vero cells with chaotic microtubules was obtained after cultivation with the excess of serum. Such cells were characterized by the increased area and exhibited slightly dispersed Golgi, whereas growth rate remained unaltered. Thus we have shown that radial organization of microtubules is not essential even for cells where it is well pronounced.

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Abbreviations

PBS:

phosphate-buffered saline

MTT:

(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide

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Authors and Affiliations

  1. Belozersky Institute of Physicochemical Biology, Moscow, 119991, Russia

    E. V. Usova, A. V. Burakov, A. A. Shpilman & E. S. Nadezhdina

  2. Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow region, 142290, Russia

    E. S. Nadezhdina

Authors
  1. E. V. Usova
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  2. A. V. Burakov
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  3. A. A. Shpilman
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  4. E. S. Nadezhdina
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Additional information

Original Russian Text © E.V. Usova, A.V. Burakov, A.A. Shpilman, E.S. Nadezhdina, 2008, published in Biofizika, 2008, Vol. 53, No. 6, pp. 972–977.

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Usova, E.V., Burakov, A.V., Shpilman, A.A. et al. Disturbance of the radial system of interphase microtubules in the presence of excess serum in cell culture medium. BIOPHYSICS 53, 523–526 (2008). https://doi.org/10.1134/S0006350908060109

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  • DOI: https://doi.org/10.1134/S0006350908060109

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