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An assessment of the models of thin filament of the sarcomere using small-angle X-ray data on rabbit relaxed muscle

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Abstract

Models of a thin filament based on various G-actin atomic structures and modes of their packing into helical structures were considered. The calculated intensities of actin layer lines were compared with the X-ray data for thin fiber bundles of a relaxed rabbit skeletal muscle. The effect of the main components of thin filament on the intensity of actin layer lines was also analyzed. The F-actin PDB 3BYH model gave the best fit to the experimental data.

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Abbreviations

Tn:

troponin

Tm:

tropomyosin

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Correspondence to N. A. Koubassova.

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Original Russian Text © N.A. Koubassova, 2008, published in Biofizika, 2008, Vol. 53, No. 6, pp. 936–942.

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Koubassova, N.A. An assessment of the models of thin filament of the sarcomere using small-angle X-ray data on rabbit relaxed muscle. BIOPHYSICS 53, 494–499 (2008). https://doi.org/10.1134/S0006350908060043

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  • DOI: https://doi.org/10.1134/S0006350908060043

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