Abstract
Fluid transport in the isolated rabbit eye lens was assayed gravimetrically, and was found to be, at least partly, an active process involving Na,K-ATPase. Thereby the pressure inside the lens proved to be elevated by 6 mm Hg. The energy required for this process was estimated at (1.5–6)·10−2 J. The movement of fluid in vivo (monitored with fluorescein) proceeds from the anterior to the posterior surface and out into the vitreous body.
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References
E. V. Mal’tsev, The Lens (Meditsina, Moscow, 1988) [in Russian].
A. Piri and R. van Geiningen, Biochemistry of the Eye (Meditsina, Moscow, 1968) [in Russian].
B. I. Bessonov and S. Buchuk, Physicochemical Bases of Transepithelial Sodium Transport (Nauka, Moscow, 1991) [in Russian].
V. Yu. Antonov, Soros. Obraz. Zh. No. 6, 14 (1997).
D. R. Eckert and D. Augustin, Animal Physiology: Mechanisms and Adaptation (Mir, Moscow, 1991) [in Russian].
D. F. Loo, E. M. Wright, and T. Zeuthen, J. Physiol. 528, 251 (2002).
R. T. Mathias, J. L. Rae, and G. J. Baldo, Physiol. Rev. 77, 21 (1997).
A. N. Yaroslavskaya, I. V. Yaroslavsky, C. Otto, et al., Biofizika 43, 125 (1998).
O. A. Candia and A. C. Zamudio, Amer. J. Cell Physiol. 282, 252 (2002).
G. S. Polunin, O. Khokvin, and A. Vegendr, Vestn. Oftal’mol. No. 4, 62 (1990).
A. P. Gal’binur, Vestn. Oftal’mol. 120,(2), 49 (2004).
J. Fischbarg, et al., Amer. J. Cell Physiol. 276, 548 (1999).
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Original Russian Text © L.V. Stepanova, G.M. Sychev, I.Yu. Marchenko, 2006, published in Biofizika, 2006, Vol. 51, No. 4, pp. 756–770.
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Stepanova, L.V., Sychev, G.M. & Marchenko, I.Y. Fluid transport in isolated rabbit eye lens. BIOPHYSICS 51, 668–670 (2006). https://doi.org/10.1134/S0006350906040245
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DOI: https://doi.org/10.1134/S0006350906040245