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Modeling of heat transfer in whole-body hyperthermia

  • Complex Systems Biophysics
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Abstract

The therapeutic application of whole-body hyperthermia, whereby the body temperature is for a short time raised to 43–44°C is currently considered quite promising. However, body temperature above 42°C also raises the risks associated with hemodynamic instability and arrhythmia. A model of heat transfer is built to improve the efficacy and safety of the immersion-convection technique of whole-body hyperthermia. The model takes into account the changes in skin blood flow and the dynamics of heart rate depending on body temperature. It adequately reflects the processes of heating in the organism and can be used to calculate the heat distribution in the body.

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References

  1. F. B. Ballyuzek, M. F. Ballyuzek, V. I. Vilenskii, et al., Controlled Hyperthermia (Nevskii Dialekt, St. Petersburg, 2001) [in Russian].

    Google Scholar 

  2. S. R. Ash, C. R. Steinhart, M. F. Curfman, et al., ASAIO J. 43(5), 830 (1997).

    Article  Google Scholar 

  3. T. Feyerabend, G. J. Wiedemann, and R. Steeves, Oncol. Rep. 8(2), 219 (2001).

    Google Scholar 

  4. H. I. Robins, D. M. Katschinski, W. Longo, et al., Cancer Chemother. Pharmacol. 43(5), 409 (1999).

    Article  Google Scholar 

  5. A. M. Westermann, E. A. Grosen, D. M. Katschinski, et al., Eur. J. Cancer 37(9), 1111 (2001).

    Article  Google Scholar 

  6. A. Zablow, L. M. Shecterle, R. Dorian, et al., Int. J. Hyperthermia 13(6), 577 (1997).

    Article  Google Scholar 

  7. E. Kano, Gan No Rinsho 33(13), 1657 (1987).

    Google Scholar 

  8. R. A. Vertrees, A. Bidani, D. J. Deyo, et al., Ann. Thorac. Surg. 70(2), 644 (2000).

    Article  Google Scholar 

  9. Z. P. Shul’man, Inzh.-Fiz. Zh. 69, 948.

  10. D. N. Kinsht and N. V. Kinsht, Informat. Systemy Upravl., No. 1(7), 43 (2004).

  11. N. V. Kinsht and D. N. Kinsht, in Second IASTED International Multi-Conference on ACIT-ASA, Ed. by Yu. I. Shokin and O. I. Potaturkin (ACTA Press, Anaheim-Calgary-Zurich, 2005), pp. 271–276.

    Google Scholar 

  12. E. Lightfoot, Transfer Phenomena in Living Systems (Mir, Moscow, 1977) [in Russian].

    Google Scholar 

  13. B. Folkov and E. Nil, Circulation (Meditsina, Moscow, 1976) [in Russian].

    Google Scholar 

  14. P. Johnson, Peripheral Circulation (Meditsina, Moscow, 1982) [in Russian].

    Google Scholar 

  15. D. Morman and L. Heller, Physiology of the Cardiovascular System (Piter, St. Petersburg, 2000) [in Russian].

    Google Scholar 

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Authors and Affiliations

  1. Novosibirsk District Hospital No. 1, Koltsovo, Novosibirsk Region, 630599, Russia

    D. N. Kinsht

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  1. D. N. Kinsht
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Original Russian Text © D.N. Kinsht, 2006, published in Biofizika, 2006, Vol. 51, No. 4, pp. 738–742.

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Kinsht, D.N. Modeling of heat transfer in whole-body hyperthermia. BIOPHYSICS 51, 659–663 (2006). https://doi.org/10.1134/S0006350906040221

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  • DOI: https://doi.org/10.1134/S0006350906040221

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