Abstract
EDAS, an alternatively spliced human gene database, contains data on alignment of proteins, mRNAs, and ESTs. For 8324 human genes, the database contains information on all observed exons and introns and also elementary alternatives formed therefrom. The database allows one to filter the output data by varying the cutoff threshold according to the significance level. The database is available at http://www.genebee.msu.ru/edas/.
Similar content being viewed by others
References
A. A. Mironov, J. W. Fickett, and M. S. Gelfand, Genome Res. 9, 1288 (1999).
D. Brett, J. Hanke, G. Lehmann, et al., FEBS Lett. 474, 83 (2000).
E. V. Kriventseva, I. Koch, R. Apweiler, et al., Trends Genet. 19, 124 (2003).
International Human Genome Sequencing Consortium, Initial sequencing and analysis of the human genome, Nature 409, 860 (2001).
D. Brett, H. Pospisil, J. Valcarcel, et al., Nature Genet. 30, 29 (2002).
FANTOM2 Consortium and the RIKEN GSC Genome Exploration Group Phase I & II Team, Analysis of the mouse transcriptome based upon functional annotation of 60,770 full length cDNAs, Nature 420, 563 (2002).
D. L. Wheeler, D. M. Church, R. Edgar, et al., Nucl. Acids Res. 32, D35 (2004).
A. A. Mironov, P. S. Novichkov, and M. S. Gelfand, Bioinformatics 17, 13 (2001).
A. Agresti, Stat. Sci. 7, 131 (1992).
A. D. Neverov, I. I. Artamonova, R. N. Nurtdinov, et al., BMC Bioinformatics 6, 266 (2005).
R. N. Nurtdinov, A. A. Mironov, and M. S. Gel’fand, Biofizika 47, 197 (2002).
R. N. Nurtdinov, I. I. Artamonova, A. A. Mironov, and M.S. Gelfand, Hum. Mol. Genet. 12, 1313 (2003).
E. O. Ermakova, Proceedings of the Second Moscow Conference on Computational Molecular Biology «MCCMB’2005» (Moscow, 2005).
V. E. Ramensky, A. D. Neverov, R. N. Nurtdinov, et al., Proceedings of the Second Moscow Conference on Computational Molecular Biology «MCCMB’2005» (Moscow, 2005).
T. A. Thanaraj, F. Clark, and J. Muilu, Nucl. Acids Res. 31, 2544 (2003).
B. Modrek and C. J. Lee, Nature Genet. 34, 177 (2003).
G. W. Yeo, E. Van Nostrand, D. Holste, et al., Proc. Acad. Sci. USA 102, 2850 (2005).
Y. Xing and C. Lee, Proc. Acad. Sci. USA 102, 13526 (2005).
Y. Xing and C. Lee, Bioinformatics 21, 3701 (2005).
B. P. Cusack and K. H. Wolfe, Mol. Biol. Evol. 22, 2198 (2005).
M. S. Gel’fand, Russ. Zh. VICh/SPID Rodstv. Probl. 8, 16 (2004).
Author information
Authors and Affiliations
Additional information
Original Russian Text © R.N. Nurtdinov, A.D. Neverov, D.B. Mal’ko, I.A. Kosmodem’yanskii, E.O. Ermakova, V.E. Ramenskii, A.A. Mironov, M.S. Gelfand, 2006, published in Biofizika, 2006, Vol. 51, No. 4, pp. 589–592.
Rights and permissions
About this article
Cite this article
Nurtdinov, R.N., Neverov, A.D., Mal’ko, D.B. et al. EDAS—A database of alternatively spliced human genes. BIOPHYSICS 51, 523–526 (2006). https://doi.org/10.1134/S0006350906040026
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1134/S0006350906040026