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On the problem of identification of intracellular signaling pathways

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Abstract

A hypothesis is proposed about the involvement of mitochondria in transduction of intracellular signals. In addition to the endoplasmic reticulum responsible for fluctuations of intracellular concentration of Ca2+, mitochondria are supposed to determine changes in the concentration of the secondary messenger cAMP. This hypothesis extends our ideas concerning mechanisms of intracellular signal transduction.

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Abbreviations

cAMP:

cyclic adenosine monophosphate

ER:

endoplasmic reticulum

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Authors and Affiliations

  1. All-Russian Research Institute of Farm Animal Genetics and Breeding, Russian Academy of Agricultural Sciences, Moskovskoe Shosse 55a, 196600, Pushkin, St. Petersburg, Russia

    V. Yu. Denisenko & T. I. Kuzmina

Authors
  1. V. Yu. Denisenko
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  2. T. I. Kuzmina
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Corresponding author

Correspondence to T. I. Kuzmina.

Additional information

Original Russian Text © V. Yu. Denisenko, T. I. Kuzmina, 2013, published in Biokhimiya, 2013, Vol. 78, No. 4, pp. 556–558.

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Denisenko, V.Y., Kuzmina, T.I. On the problem of identification of intracellular signaling pathways. Biochemistry Moscow 78, 431–432 (2013). https://doi.org/10.1134/S0006297913040135

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  • DOI: https://doi.org/10.1134/S0006297913040135

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