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The centrosome is a polyfunctional multiprotein cell complex

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Abstract

Contemporary knowledge about centrosome proteins and their ensembles, which can be divided into several functional groups—microtubule-nucleating proteins, microtubule-anchoring proteins, centriole-duplication proteins, cell cycle control proteins, primary cilia growth regulation proteins, and proteins of regulation of cytokinesis—is reviewed. Structural—temporal classification of centrosomal proteins and the scheme of interconnection between the different centrosomal protein complexes are presented.

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Abbreviations

AB:

antibody

MT:

microtubule

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  1. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992, Moscow, Russia

    I. B. Alieva & R. E. Uzbekov

  2. Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119992, Moscow, Russia

    R. E. Uzbekov

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Original Russian Text © I. B. Alieva, R. E. Uzbekov, 2008, published in Biokhimiya, 2008, Vol. 73, No. 6, pp. 782–803.

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Alieva, I.B., Uzbekov, R.E. The centrosome is a polyfunctional multiprotein cell complex. Biochemistry Moscow 73, 626–643 (2008). https://doi.org/10.1134/S0006297908060023

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