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Biochemistry (Moscow)

, Volume 72, Issue 10, pp 1151–1160 | Cite as

Nitrate reductases: Structure, functions, and effect of stress factors

  • E. V. Morozkina
  • R. A. Zvyagilskaya
Review

Abstract

Structural and functional peculiarities of four types of nitrate reductases are considered: assimilatory nitrate reductase of eukaryotes, as well as cytoplasmic assimilatory, membrane-bound respiratory, and periplasmic dissimilatory bacterial nitrate reductases. Arguments are presented showing that eukaryotic organisms are capable of nitrate dissimilation. Data concerning new classes of extremophil nitrate reductases, whose active center does not contain molybdocofactor, are summarized.

Key words

nitrate reductase nitrification denitrification molybdenum molybdenum cofactor molybdopterin-guanine dinucleotides stress 

Abbreviations

DMSO

dimethyl sulfoxide

Euk-NR

eukaryotic assimilatory NRase

MGD

molybdopterin-guanine dinucleotide

Mo

molybdenum

Mo-co

molybdenum cofactor

Nap

periplasmic dissimilatory NRase

Nar

membrane-bound respiratory NRase

Nas

cytoplasmic assimilatory NRase

NRase

nitrate reductase

TMAO

trimethylamine N-oxide

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© Pleiades Publishing, Ltd. 2007

Authors and Affiliations

  1. 1.Bach Institute of BiochemistryRussian Academy of SciencesMoscowRussia

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