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Enantiospecific Sorption of L-Lysin by Molecularly Imprinted Sorbents Based on Methacrylic Acid and Ethylene Glycol Dimethacrylate

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Abstract

L-lysine-imprinted polymeric sorbents based on methacrylic acid and ethylene glycol dimethacrylate have been synthesized. The equilibrium and kinetics of amino acid sorption on the synthesized sorbents and control sorbent (a nonimprinted analog) are compared. It is shown that the enantioselective separation of the D,L-lysine racemic mixture was most effectively performed on polymeric sorbent synthesized in the presence of 6 mol % L-lysine. The amino acid was fixed on the surface layer of this sorbent at energy-equivalent, specific binding sites.

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The authors declare that they have no conflict of interest. This article does not contain any studies involving animals or human participants performed by any of the authors.

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Correspondence to I. V. Polyakova.

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Translated by A. Levina

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Polyakova, I.V., Pisarev, O.A. Enantiospecific Sorption of L-Lysin by Molecularly Imprinted Sorbents Based on Methacrylic Acid and Ethylene Glycol Dimethacrylate. Appl Biochem Microbiol 55, 107–111 (2019). https://doi.org/10.1134/S0003683819010137

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  • DOI: https://doi.org/10.1134/S0003683819010137

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